Identification and interpretation of longitudinal gene expression changes in trauma.

Rationale: The relationship between leukocyte gene expression and recovery of respiratory function after injury may provide information on the etiology of multiple organ dysfunction.

Objectives: To find a list of genes for which expression after injury predicts respiratory recovery, and to identify which networks and pathways characterize these genes.

Methods: Blood was sampled at 12 hours and at 1, 4, 7, 21 and 28 days from 147 patients who had been admitted to the hospital after blunt trauma.

Past and present midwifery education in Turkey.

Among criteria relating to the level of development in a country are health indicators such as total fertility, maternal mortality, infant mortality, and rates of life expectancy at birth. These have a close relationship with the quality of health-care services, especially those provided by midwives. An improvement in midwifery services can be achieved to a great extent by standardised and high-quality midwifery education.

Degradation of vincristine by myeloperoxidase and hypochlorous acid in children with acute lymphoblastic leukemia.

Vincristine (VCR) is an effective drug against acute lymphoblastic leukemia (ALL), many solid tumors, but not acute myeloid leukemia. It has been hypothesized that resistance of myeloblasts to VCR is related to myeloperoxidase (MPO) and production of hypochlorous acid (HOCl). We investigated the relationship between VCR degradation and MPO expression and serum HOCl concentrations in pediatric patients with ALL, lymphoma and solid tumors.