Publications by authors named "Aysun Sarıcetin"
Objectives: The aim of this study was to evaluate the effects of inhaled fluticasone propionate on wound healing after phonosurgical trauma of larynx in rabbit model.
Study Design: A randomized controlled study on experimental animals (rabbits).
Methods: In this prospective experimental animal study, surgically induced type 2 scar was created under general anesthesia in 52 vocal folds of 26 rabbits.
Purpose: Continuous oxygen therapy to compensate for decreased oxygen saturation in the blood is a life-saving treatment used in case lung involvement. Excess oxygen delivery was reported to be a common situation, in which about 50% of the patients showed hyperoxemia and 4% in severe hyperoxemia. In this work, we investigated the effects of hyperoxia on the rat kidneys and whether tadalafil has an effect to reduce this damage.
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- The study looked at how tadalafil, a medicine, helps protect against damage caused by too much oxygen in rats.
- Rats were divided into three groups: one group got no treatment, one group was exposed to high oxygen, and the last group got high oxygen plus tadalafil.
- The results showed that while high oxygen increased some protective enzymes in the body, giving tadalafil made those levels go down and also reduced some symptoms in the rats' body parts.