Publications by authors named "Aysun Ayaz Sarı"
Article Synopsis
- The study investigates the relationship between language impairments and central auditory processing difficulties in children with self-limited epilepsy characterized by centrotemporal spikes, examining how these issues relate to seizure timing and neuropsychiatric aspects.
- Two groups of patients based on seizure timing underwent various assessments, revealing that both groups performed significantly worse on auditory processing tests compared to healthy controls, with some differences in expressive language scores.
- Findings indicate that children experiencing seizures at night may show more behavioral issues and impulsivity compared to those with seizures in the morning, highlighting the complex interactions between epilepsy, language, and neuropsychiatric functioning.
Background: Purine nucleoside phosphorylase (PNP) deficiency is a rare autosomal recessive combined immunodeficiency. The phenotype is profound T cell deficiency with variable B and NK cell functions and results in recurrent and persistent infections that typically begin in the first year of life. Neurologic findings occur in approximately two-thirds of patients.
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