Publications by authors named "Aysha Bano"
Background: Emerging literature has suggested the antiepileptic activity of cysteine leukotriene receptor (CysLTR) antagonists in experimental animals of epilepsy. Leukotrienes are substances that cause inflammation and affect brain activity, blood flow, oxidation, and inflammation in the brain. These processes are related to epilepsy and its complications.
View Article and Find Full Text PDFArticle Synopsis
- Emerging studies suggest that benzimidazole-based anthelmintics (BBA) may have anticancer effects against lung cancer, but the exact mechanisms are not yet understood.
- Researchers utilized network pharmacology and molecular docking to identify potential molecular mechanisms and targets for BBA, gathering extensive data from various scientific databases to construct protein-protein interaction diagrams.
- The analysis identified key targets such as cyclin D1 and EGFR, with ricobendazole ranked as the most promising BBA for lung cancer treatment, indicating a need for further research in this area.
Topical application of BRAF inhibitors has been shown to accelerate wound healing in murine models, which can be extrapolated into clinical applications. The aim of the study was to identify suitable pharmacological targets of BRAF inhibitors and elucidate their mechanisms of action for therapeutic applicability in wound healing, by employing bioinformatics tools including network pharmacology and molecular docking. The potential targets for BRAF inhibitors were obtained from SwissTargetPrediction, DrugBank, CTD, Therapeutic Target Database, and Binding Database.
View Article and Find Full Text PDF