Publications by authors named "Aysha Al Malki"
Article Synopsis
- Spiroadenomas are rare, benign skin tumors from sweat glands, often appearing as single nodules on the head, neck, and trunk, while their malignant counterpart, Spiradenocarcinoma (MSA), is extremely rare and aggressive, commonly affecting those over 50.
- A 69-year-old woman with a health history including diabetes and hypertension presented multiple skin swellings, undergoing initial excisions that initially misidentified the lesions before the eventual diagnosis of MSA in 2022.
- Surgical excision remains the standard treatment for MSA, with an emphasis on wide local excision to reduce metastasis risk, while close monitoring is crucial for identifying recurrences or further spread of
IL-36 is a most recent member of the IL-1 cytokine family, primarily expressed at barrier sites of the body such as the skin, lungs, and intestine. It plays a vital role in inflammation and is implicated in the development of various cutaneous; intestinal; and pulmonary disorders, including psoriasis, inflammatory bowel disease, and chronic obstructive pulmonary disease. IL-36 comprises 4 isoforms: the proinflammatory IL-36α, IL-36β, and IL-36γ and the anti-inflammatory IL-36R antagonist.
View Article and Find Full Text PDFNeuroimmune communication regulating pruritus in atopic dermatitis.
J Allergy Clin Immunol
June 2022
Atopic dermatitis (AD) is a common, chronic-relapsing inflammatory skin disease with significant disease burden. Genetic and environmental trigger factors contribute to AD, activating 2 of our largest organs, the nervous system and the immune system. Dysregulation of neuroimmune circuits plays a key role in the pathophysiology of AD, causing inflammation, pruritus, pain, and barrier dysfunction.
View Article and Find Full Text PDFRapidly involuting congenital hemangioma is a subtype of congenital hemangioma. Ulceration and bleeding are rarely reported in rapidly involuting congenital hemangioma, with only four cases reported in the literature to our knowledge. We describe a case of a newborn girl who presented with rapidly involuting congenital hemangioma complicated by ulceration and severe bleeding and discuss treatment.
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