Effects of Mucuna pruriens on Free Fatty Acid Levels and Histopathological Changes in the Brains of Rats Fed a High Fructose Diet.

Objective: To investigate free fatty acid levels and histopathological changes in the brain of rats fed a high fructose diet (HFrD) and to evaluate the effects of Mucuna pruriens, known to have antidiabetic activity, on these changes.

Materials And Methods: The study comprised 28 mature female Wistar rats. The rats were divided into 4 groups, each included 7 rats.

Can Behenic Acid (C22:0) Levels be a Prognostic Factor in Glial Tumors?

Background: Inhibition of fatty acid synthase leads to apoptosis in cancers, which leads to high levels of fatty acid synthesis. This indicates that cancer cells depend on fatty acid in order to survive. In this study, we investigated whether or not there was a relationship between the glial tumor grade and free fatty acid level of tumor tissue.

Electrophysiological effects of bosentan in rats with induced cerebral ischemia-reperfusion.

We examined the effect of bosentan, an ETA and ETB receptor antagonist, on EEG, an indicator of neuronal activity, in rats with experimentally induced cerebral ischemia-reperfusion. The rats were divided into three groups with seven rats in each group. Before the procedures, the EEGs of all rats were recorded for ten minutes.

Accuracy of sphygmomanometers at pharmacies.

Background/aims: The aims of this study are to assess the reasons of using sphygmomanometers at pharmacies and to evaluate their accuracy.

Methods: 135 devices (118 aneroid, 1 mercury, and 16 automated) from 125 pharmacies (located in Samsun city center) were included in the study. A non-randomized, cross-sectional design was used for the study protocol which had two parts: assessment of devices and a questionnaire about the pharmacy and present sphygmomanometer(s).

Effects of transfer from the operating room to the intensive care unit after cardiac surgery on hemodynamics and blood gases.

Objective: To evaluate the effect of transferring open-heart surgery patients from the operating room to the intensive care unit on hemodynamic parameters and blood gases.

Methods: The study was conducted as a prospective, observational study at the German Hospital, Istanbul, Turkey in 2007. Hemodynamic, blood gas values, and oxygen saturation measured by pulse oximetry (SpO 2) values were recorded in 37 patients who had undergone open-heart surgery.

Melatonin attenuates renal ischemia-reperfusion injury in nitric oxide synthase inhibited rats.

Recent studies show that melatonin reduces the blood pressure (BP) and ischemia/reperfusion (I/R)-induced damage. This study was designed to investigate the effects of melatonin on the renal I/R injury in rats given the nitric oxide synthase (NOS) inhibitor, N(omega)-nitro-L-arginine methyl ester (L-NAME). After right nephrectomy, I/R was induced by occlusion of the left renal vessels for 60 min, followed by 24h reperfusion.