Publications by authors named "Aysegul Y Tahiroglu"

Objective: Pineal gland volume (PGV), which is associated with sleep and circadian rhythm, is known to be changed in some psychiatric disorders such as major depression, mood disorders and schizophrenia. This study aimed to compare the PGV of children with mild and moderate intellectual disability (ID) and healthy children.

Methods: This multicentre retrospective study included 40 children with ID (patient group), aged 6-12 years and 40 age- and sex-matched healthy children (control group).

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Article Synopsis
  • About half of childhood and adolescent cases of obsessive-compulsive disorder (OCD) have symptoms that persist into adulthood, and a study suggests that immunologic stress may increase the risk of developing OCD in childhood.
  • Researchers analyzed the MHC complex I and II alleles in 49 children with OCD and 277 healthy peers, using various statistical methods to interpret their findings.
  • The study identified specific alleles (A2, A29, C4, DRB3.1, and DRB1*16) that are associated with a higher risk of developing OCD, and it highlights a potential link between MHC genes and OCD that reflects similar associations found in autoimmune disorders.
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Background: The impaired regulation of emotional responses has significant social consequences for patients with attention deficit hyperactivity disorder (ADHD) and can be thought to increase the risk for technological addictions.

Aim: Ditto objective of the present research is to investigate the relationship between technological addictions and trait emotional intelligence (EI) in adolescents with ADHD.

Methods: This cross-sectional study was conducted in 150 treatment-naïve adolescents with ADHD, aged 12-18 years.

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Introduction: Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), a subgroup of obsessive-compulsive disorder (OCD), has received much attention even though the specific underlying mechanisms remain unknown. Mannose-binding lectin (MBL) is a key factor in the innate immune response. The aim of this study was to investigate the role of MBL2 gene polymorphisms in pediatric OCD patients diagnosed as PANDAS, PANDAS-Variant and non-PANDAS.

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Article Synopsis
  • The study aimed to assess the prevalence of affective disorders in a representative sample of Turkish students from second to fourth grades.
  • A total of 5,842 participants were analyzed, revealing a 2.5% prevalence of affective disorders, with major depressive disorder (MDD) being the most common at 1.06%.
  • The findings suggest the need for early interventions, particularly for children with family risk factors like maternal psychopathology and paternal illness.
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Purpose: Individuals with attention deficit/hyperactivity disorder (ADHD) may suffer from emotional dysregulation (ED), although this symptom is not listed among the diagnostic criteria. Methylphenidate (MPH) is useful in reducing emotional symptoms in ADHD. The aim of the present study was to determine both psychosocial risk factors and presence of ED in adolescents with ADHD before and after MPH treatment.

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Objectives: Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) is a newly defined disease in neuropsychiatry and occurs with an autoimmune mechanism after Group A Beta Hemolytic Streptococcus (GABHS) infection. Tumor necrosis factor (TNF), encoded by TNF-α gene has an important role in the apoptotic mechanisms of autoimmune diseases. Recently, TNF-α polymorphisms and autoimmune/psychiatric disorders have been reported to be related.

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There are many comorbid disorders associated with autism spectrum disorders in child and adolescent population. Although obsessive compulsive disorder and autism spectrum disorders (ASD) comorbidity has common in clinical practice, there are few reports about psychopharmacological treatment for obsessive compulsive symptoms in children with ASD in the literacy. We report a successful treatment case with aripiprazole in Asperger's Disorder with obsessive compulsive symptoms.

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The purpose of this study was to determine the socio-demographic characteristics of sexually abused children. The records of 101 cases of child sexual abuse (CSA) were retrospectively evaluated. Socio-demographic characteristics of the victims, type of sexual abuse, and psychiatric diagnosis were studied.

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Objective: The main aim of the present study is to investigate the short-term cognitive effects of computer games in children with different psychiatric disorders and normal controls.

Method: One hundred one children are recruited for the study (aged between 9 and 12 years). All participants played a motor-racing game on the computer for 1 hour.

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The aim of this study was to investigate Internet use habits and problematic Internet use (PIU) in Turkish adolescents. Participants were 3,975 undergraduate students, 7.6% of whom used the Internet for more than 12 hours weekly.

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Extrapyramidal symptoms (EPSs) (dystonic reaction, rigidity, and akathisia) occur as a result of D2 receptor blockade. Selective serotonin-reuptake inhibitors (SSRIs) have been reported to induce extrapyramidal signs and symptoms but tricyclic antidepressants have been rarely reported. Among the side effects attributed to valproic acid administration, the production of EPS is very rare, particularly in children.

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Feeding disorders of infancy or early childhood are relatively uncommon in the pediatric population. In posttraumatic eating disorder, the infant demonstrates food refusal after a traumatic event or repeated traumatic events to the oropharynx or esophagus. We present case reports of 24-month-old twin girls, A and B, who presented to our clinic with food refusal and fear of feeding.

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Synopsis of recent research by authors named "Aysegul Y Tahiroglu"

  • - Aysegul Y Tahiroglu's research primarily focuses on the intersection of psychiatric disorders in children and adolescents, specifically exploring conditions like obsessive-compulsive disorder (OCD), attention deficit hyperactivity disorder (ADHD), and their comorbidities, alongside genetic and environmental factors influencing these conditions.
  • - Recent studies by Tahiroglu have identified potential genetic links between major histocompatibility complex (MHC) alleles and childhood OCD, while also investigating the role of emotional intelligence in technological addictions among adolescents with ADHD.
  • - Additionally, her work has addressed the prevalence of affective disorders in Turkish children and the impact of treatments like methylphenidate on emotional dysregulation in ADHD, highlighting the complexity and interrelation of psychogenic factors in childhood mental health.