Publications by authors named "Aysegul Seremet Keskin"

Article Synopsis
  • Extended-spectrum beta-lactamase-producing (ESBL-E) infections significantly impact patients with hematologic cancers, particularly those with prior colonization by resistant bacteria, leading to optimized treatments using carbapenems.
  • A study comparing empirical carbapenem therapy to non-carbapenem therapy in hospitalized adult hematology patients showed that 36% had positive ESBL-E colonization, yet the rate of future infections did not significantly differ between colonized and non-colonized patients.
  • Despite the presence of ESBL-E, there were no significant mortality rates associated with these infections, indicating that factors beyond colonization status may influence patient outcomes.
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Article Synopsis
  • The study investigated the vaccination status and risk factors for ICU support among inpatients with breakthrough COVID-19 infections, categorizing them as fully or partially vaccinated.
  • A total of 516 patients were analyzed, revealing that hypertension, diabetes, and coronary artery disease were common comorbidities, with fully vaccinated patients showing a significantly lower need for ICU support.
  • The findings suggest that older age, specific health conditions, and incomplete vaccination increase the likelihood of requiring ICU care, highlighting the need for ongoing monitoring and booster vaccinations for at-risk populations.
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Article Synopsis
  • The study investigates the role of angiopoietin-2 levels in COVID-19 patients and their association with the need for intensive care unit (ICU) hospitalization.
  • It involved 180 patients, with 43 requiring ICU care and findings showing significantly higher angiopoietin-2 levels in those patients (p = 0.018).
  • Angiopoietin-2 levels may help predict ICU hospitalization, with a specific cut-off value of 64.5 ng/L, but the sensitivity was moderate (59%) and specificity was low (42%).
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Introduction: We aimed to examine the D-dimer/platelet ratio (DPR), which includes the combination of D-dimer and platelet measurements, which are two important markers in predicting prognosis, considering that it will show clinical progression.

Methods: After ranking the patients from high to low according to DPR level, they were divided into three equal groups. Demographic, clinical, and laboratory parameters between groups were compared according to DPR level.

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/. Coronavirus disease 2019 (COVID-19) is a life-threatening disease characterized by a prothrombotic state. Because homocysteine (Hcy) is a potential biomarker in thrombotic disease, this article aims to highlight the role of Hcy in the prognosis of COVID-19 pneumonia.

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Background Intra-abdominal contamination is a critical risk factor for candidemia. Because of the high mortality of candidemia and delayed results of cultures, preventive antifungal (AF) treatment can be administered. Especially in the intensive care unit (ICU), it may be necessary to determine the preventive AF approach due to the poor clinical condition of the patients.

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Background: COVID-19 and solid cancer are both associated with an increased risk of thromboembolism.

Objectives: Assess whether solid cancer is a risk factor for acute ischemic event development among patients with COVID-19.

Design: Retrospective cohort SETTING: A tertiary training and research hospital PATIENTS AND METHODS: Patients who were hospitalized for COVID-19 for ≥3 days between 15 March 2020 and 30 March 2021 at Antalya Training and Research Hospital, Antalya, Turkiye.

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Introduction: Although vaccines are the safest and most effective means to prevent and control infectious diseases, the increasing rate of vaccine hesitancy and refusal (VHR) has become a worldwide concern. We aimed to find opinions of parents on vaccinating their children and contribute to available literature in order to support the fight against vaccine refusal by investigating the reasons for VHR on a global scale.

Methodology: In this international cross-sectional multicenter study conducted by the Infectious Diseases International Research Initiative (ID-IRI), a questionnaire consisting of 20 questions was used to determine parents' attitudes towards vaccination of their children.

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The tetanus vaccine is not routinely given to Turkish adults. Protective tetanus immunity decreases with age. Health-care personnel (HCPs), who are role models in the field of health, are a target group in order to achieve a higher rate of tetanus vaccination in the community.

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Background/aim: As the experience has increased regarding SARS-CoV-2 in time, treatment trends have changed since the beginning of the pandemic. This study aimed to compare the outcomes of different treatment modalities for inpatients in a tertiary pandemic hospital in Antalya, Turkey.

Materials And Methods: Individuals aged 18 years and above who tested positive for SARS-CoV-2 in PCR with presenting COVID-related radiological findings, hospitalized for at least 3 days, and completed follow-up between March 15, 2020 and November 30, 2020 were included in the study.

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Post-operative nosocomial meningitis is a critical complication that develops in patients after neurosurgical interventions and operations. Data were collected for 65 patients who were diagnosed as having nosocomial meningitis after neurosurgery. The agent profile, clinical and biochemical differences in gram-negative and gram-positive meningitis, and the effectiveness of intrathecal antibiotic administration in cases with carbapenem-resistant gram-negative agents were evaluated.

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Background: This study aimed to investigate the prevalence of the disease and testing and vaccination status of healthcare workers in terms of hepatitis A infection as well as their awareness. This study is a multicenter descriptive study performed with healthcare workers.

Material And Methods: Testing status for hepatitis A, awareness of the results and vaccination status of healthcare workers were compared.

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Aim: Influenza vaccination is the most effective method in prevention of influenza disease and its complications. Our study aimed to investigate the rates of vaccination and the behaviours and attitudes against the vaccine in healthcare workers in Turkey.

Methods: This multicentre national survey is a descriptive study in which 12 475 healthcare workers.

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This study was performed to compare the mortality associated with carbapenem-resistant Acinetobacter baumannii (CRAB) and carbapenem-sensitive A. baumannii (CSAB) infections, to identify potential risk factors for CRAB infections, and to investigate the effects of potential risk factors on mortality in CRAB and CSAB patients. This retrospective case-control study was conducted in a university hospital between January 1, 2005 and December 30, 2006.

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Intravenous catheterization can lead to colonization as well as a broad spectrum of infections ranging from catheter site infections to catheter-related blood stream infections (CRBSIs). The aim of this study was to evaluate the distribution of causative agents and their antibiotic susceptibility patterns in CRBSIs and catheter site infections along with the colonization rates and colonizing microorganisms in Zonguldak Karaelmas University Hospital, Turkey. The results of cultures from catheter tips and/or intracatheter blood cultures and simultaneously taken peripheral blood cultures were sent to medical microbiology laboratory and were retrospectively investigated for 201 patients hospitalized between September 2007 and September 2009.

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Visceral leishmaniasis (VL) which is a chronic disease caused by the protozoon, Leishmania, occurs widely worldwide and it is widespread in most of the countries in the Mediterranean basin. The infection which is transmitted by a sandfly (Phlebotomus) vector, has a prolonged incubation period and insidious onset. VL generally affects children and may be fatal if not treated.

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Objective: Empirical beta-lactam monotherapy has become the standard therapy in febrile neutropenia. The aim of this study was to compare the efficacy and safety of piperacillin-tazobactam versus carbapenem therapy with or without amikacin in adult patients with febrile neutropenia.

Methods: In this prospective, open, single-center study, 127 episodes were randomized to receive either piperacillin-tazobactam (4 x 4.

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Community-acquired pneumonia (CAP) is a common infectious disease with high morbidity and mortality. In this study, demographic features, underlying conditions, causative pathogens and factors affecting length of hospital stay and mortality were retrospectively investigated in patients who were diagnosed as CAP and followed-up in our unit between January 2005-December 2007. Among 97 patients 65 (67%) were male, 32 (33%) were female and the mean age was 62.

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