Publications by authors named "Aysegul Kose"

1,2,3-Triazole compounds () and their oxime derivatives () were synthesized. The structures of these synthesized compounds were characterized using common spectroscopic methods. Crystal structures of the compounds and were determined by single crystal X-ray diffraction studies.

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The synthesis of benzimidazole compounds containing benzophenone group in accordance with the literature and the investigation of DNA binding properties of these compounds by using UV-vis and photoluminescence spectroscopy methods constitute the basis of this research. The structures of the compounds were determined by methods such as FT-IR, H, C NMR, UV-, Photoluminescence spectroscopy, and X-ray crystallography. By using methods such as UV-, Photoluminescence spectroscopy, and viscosity tests, information were collected about the binding types, binding mode, and binding energies of the compounds with DNA.

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Special attention is given to the development of rapid and sensitive detection of nitroaromatic explosives for homeland security and environmental concerns. As part of our contribution to the detection of nitroaromatic explosives, fluorescent materials (A), (B) and (C) were synthesized from the reaction of 1,2-diaminocyclohexane with pyrene-1-carbaldehyde, anthracene-9-carbaldehyde and 2-hydroxy-1-naphthaldehyde, respectively. The structures of the prepared fluorescent azomethine probes were confirmed using FTIR, H-NMR and C-NMR spectroscopies.

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In this study, Schiff base compounds (1-5) were synthesized by the reaction of 5-amino-1,10-phenanthroline with various aldehydes. The molecular structures of the synthesized compounds were characterized by FT-IR, H/C NMR and mass spectroscopic methods. Single crystals of 1 were obtained and their molecular structures in crystalline form were determined by single crystal X-ray diffraction study.

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In this study, two chiral Schiff base ligands (L1 and L2) were synthesized from the condensation reaction of (S)-2-amino-3-phenyl-1-propanol with 2-hydroxybenzaldehyde and 2-hydroxy-1-naphthaldehyde as metal precursors for the preparation of transition metal complexes with Pd(II), Fe(II), Ni(II) and Cu(II). The compounds were characterized by using X-ray (for L1-Pd(II)), NMR, FT-IR, UV-Vis, magnetic susceptibility, molar conductivity, and elemental analysis. The in vitro cytotoxic effects of ligands (L1 and L2) and their metal complexes on colon cancer cells (DLD-1), breast cancer cells (MDA-MB-231) and healthy lung human cell lines were investigated by using the 3-(4,5-dimethylthiazol-2-yl)-2,5‑diphenyl tetrazolium bromide (MTT) assay.

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