KRAS, BRAF, PIK3CA mutation frequency of radical prostatectomy samples and review of the literature.

Objective: The molecular basis of prostate cancer is highly heterogeneous. Our study aimed to perform the mutation analysis of , and immunohistochemical (IHC) evaluation of EGFR, HER2, p16, and PTEN to demonstrate new areas for targeted therapies.

Methods: A total of 24 prostatectomy samples diagnosed with adenocarcinoma were analyzed by microarray hybridization.

Acupuncture on Yintang point decreases preoperative anxiety.

Objectives: The aim of this study was to investigate the effect of ear-press needle acupuncture on Yintang point for preoperative anxiety.

Design: This was a prospective, randomized, single-blind, controlled study.

Settings/location: The study setting was the Department of Anesthesiology in Ankara Training and Research Hospital of Ministry of Health, Ankara, Turkey.

Anesthesia in multiple sclerosis and obstructive sleep apnea: case report and literature review.

While patients with obstructive sleep apnea (OSA) or multiple sclerosis (MS) are at high risk of developing postoperative complications, both of them have special anesthetic considerations in intraoperative and postoperative periods. A careful preoperative evaluation, use of the optimal anesthetic regimen and close postoperative care is essential for these patients. Rarity of coexistence of both obstructive sleep apnea and multiple sclerosis in a surgical patient necessitates careful anesthetic management.

Postoperative analgesic efficacy of intravenous dexketoprofen in lumbar disc surgery.

Background: We investigated the postoperative analgesic efficacy and effect on total tramadol consumption of intravenous dexketoprofen trometamol, a new nonsteroidal anti-inflammatory drug, in patients that had undergone lumbar disc surgery.

Methods: Sixty patients were included in this placebo-controlled, randomized, double-blind study. General anesthesia was applied to both groups.

The efficacy of ilioinguinal and iliohypogastric nerve block for postoperative pain after caesarean section.

Background: The effect of ilioinguinal and iliohypogastric (II-IH) nerve block on postoperative pain is well documented when performed before Caesarean section (CS) but the efficacy remains unclear when performed after the surgical procedure. The aim of this study is to investigate the effect of II-IH nerve block on postoperative pain and analgesic consumption in patients when performed after CS.

Methods: Sixty ASA I- II patients, scheduled for elective CS were included in the study.

The analgesic effect of 8 and 16 mg lornoxicam administered before shock wave lithotripsy: a randomized, double-blind, controlled study.

Objectives: To evaluate the efficacy of 2 different doses of intravenous lornoxicam for pain relief during shock wave lithotripsy (SWL).

Methods: In this randomized, controlled, double-blind study, 60 ASA I-II patients undergoing SWL were randomly divided into 3 groups. Fifteen minutes before SWL, 4 mL of saline solution was given to the patients in group I, 8 mg lornoxicam in group II, and 16 mg lornoxicam in group III.