Temporal patterns for inguinal hernia recurrence operations after Shouldice Repair.

Purpose: Shouldice Repair for inguinal hernias results in a low recurrence rate; however, little is known about the risk factors for these relapses. In the present study, we reviewed all patient's undergoing a reoperation for recurrence after a primary Shouldice Repair.

Methods: Patients undergoing recurrent inguinal hernia repair from 2013 to 2017 were identified.

Incidence of opioid use and early postoperative pain intensity after primary unilateral inguinal hernia repair at a single-center specialty hospital.

Purpose: This research examined opioid use, pain intensity, and pain management after primary unilateral inguinal hernia repair (PUIHR) at a single-center specialty hospital.

Methods: After research, ethics board approval, and informed consent, pain scores (0-10 numerical rating scale [NRS]) were obtained from survey-based questionnaires administered at the pre- and 3-day postoperative timepoints. Descriptive results are presented as frequency, mean, standard deviation, range, median, and interquartile ranges, as appropriate.

On the Mechanism of Human Saliva Interaction with Environmental Dust in Relation to Spreading of Viruses.

Environmental effects such as dust mitigation can amplify the spread of viruses via inhaling infected dust particles. Infusion and the spreading rate of human saliva over the dust particles can play a critical role in contiguous virus spread. In the present study, mechanical and chemical interactions of human saliva with environmental dust particles are considered.

Activation of GATA4 gene expression at the early stage of cardiac specification.

Currently, there are no effective treatments to directly repair damaged heart tissue after cardiac injury since existing therapies focus on rescuing or preserving reversibly damaged tissue. Cell-based therapies using cardiomyocytes generated from stem cells present a promising therapeutic approach to directly replace damaged myocardium with new healthy tissue. However, the molecular mechanisms underlying the commitment of stem cells into cardiomyocytes are not fully understood and will be critical to guide this new technology into the clinic.

Impaired dopaminergic neuron development and locomotor function in zebrafish with loss of pink1 function.

Mutations in the human PTEN-induced kinase 1 (PINK1) gene are linked to recessive familial Parkinson's disease. Animal models of altered PINK1 function vary greatly in their phenotypic characteristics. Drosophila pink1 mutants exhibit mild dopaminergic neuron degeneration and locomotion defects.