Publications by authors named "Ayse Tasdemir"
Article Synopsis
- Liver fibrosis results from chronic liver inflammation leading to excess extracellular-matrix production by activated hepatic stellate cells (HSCs), which can lead to serious liver damage.* -
- Research on mice showed that lacking HIF-prolyl-hydroxylase 1 (PHD1) reduced liver fibrosis severity and related inflammation, while treatment with the inhibitor DMOG did not prevent fibrosis.* -
- PHD1 deficiency was linked to decreased activation of HSCs and lower expression of fibrotic and inflammatory markers, suggesting that targeted PHD1 inhibitors might be effective in managing liver fibrosis.*
Bakırçay is one of the important rivers of Western Anatolia, Türkiye. The objectives of this study are (a) to determine the diversity of benthic invertebrates distributed in Bakırçay, (b) to evaluate the obtained data using various biological indices, (c) to determine the interactions of species with environmental variables, and (d) to estimate the water quality level of the river using BMWP and ASPT analyses. Samplings were carried out at 15 stations between October 2017 and July 2018, seasonally.
View Article and Find Full Text PDFBackground: Most patients with hip fractures are elderly patients with comorbidities, and well-managed pain management is associated with positive postoperative outcomes. In recent years, new indications for regional anesthesia techniques have been defined, and they have found more place in clinical practice. Herein we investigate the effect of US-guided PENG block on positioning pain and compare that effect to intravenous opioid in patients undergoing surgery under spinal anesthesia for hip fractures.
View Article and Find Full Text PDFThe current study presents a comprehensive taxonomic list of the Chironomidae family in Turkey. The research involved an extensive literature review, resulting in the hierarchical classification of 7 out of the 11 subfamilies. The checklist encompasses 408 chironomid taxa belonging to 128 genera.
View Article and Find Full Text PDFBackground: Kidney transplantation is the predominant treatment option in patients with end-stage renal disease. The aim of this study was to evaluate the effect of the presence of a psychiatric disorder on the quality of life in children and adolescents after kidney transplantation.
Methods: A total of 43 patients aged 6 to 18 years were included in the study.