Effects of ceragenins and conventional antimicrobials on Candida albicans and Staphylococcus aureus mono and multispecies biofilms.

It is known that synergy between Candida albicans and Staphylococcus aureus results in enhanced biofilm formation and increased resistance to antimicrobials. Ceragenins (CSAs) are derivatives of cholic acid designed to mimic the antimicrobial activities of endogenous antimicrobial peptides. In this study, various CSAs were tested on C.

activities of antifungals alone and in combination with tigecycline against biofilms.

Background: may form biofilms, which are thought to underlie the most recalcitrant infections.

Methods: In this study, activities of antifungal agents alone and in combination with tigecycline against planktonic cells and mature and developing biofilms of isolates were evaluated.

Results: Amphotericin B and echinocandins were found to be the most effective agents against mature biofilms, whereas the least effective agent was fluconazole.

Antimicrobial activities of widely consumed herbal teas, alone or in combination with antibiotics: an study.

Background: Because of increasing antibiotic resistance, herbal teas are the most popular natural alternatives for the treatment of infectious diseases, and are currently gaining more importance. We examined the antimicrobial activities of 31 herbal teas both alone and in combination with antibiotics or antifungals against some standard and clinical isolates of , , , , , methicillin susceptible/resistant and .

Methods: The antimicrobial activities of the teas were determined by using the disk diffusion and microbroth dilution methods, and the combination studies were examined by using the microbroth checkerboard and the time killing curve methods.

Solvent-Free Microwave-Assisted Extraction of Polyphenols from Olive Tree Leaves: Antioxidant and Antimicrobial Properties.

Response surface methodology (RSM) and artificial neural networks (ANN) were evaluated and compared in order to decide which method was the most appropriate to predict and optimize total phenolic content (TPC) and oleuropein yields in olive tree leaf () extracts, obtained after solvent-free microwave-assisted extraction (SFMAE). The SFMAE processing conditions were: microwave irradiation power 250-350 W, extraction time 2-3 min, and the amount of sample 5-10 g. Furthermore, the antioxidant and antimicrobial activities of the olive leaf extracts, obtained under optimal extraction conditions, were assessed by several in vitro assays.

Investigation of preservative efficacy and microbiological content of some cosmetics found on the market.

In this study, microbial content and preservative efficacy of various cosmetic products, which are produced and sold in markets of our country, were investigated. Microbial content and preservative efficacies of products were investigated according to United States Pharmacopeia (USP) method. Microorganism counts of out 14 of 93 cosmetic products were recovered in the range between 1.

Postantibiotic effect of various antibiotics on Legionella pneumophila strains isolated from water systems.

The postantibiotic effects (PAE) of azithromycin, clarithromycin, ciprofloxacin, and levofloxacin were investigated against Legionella pneumophila (L. pneumophila) strains isolated from several hot water systems of different buildings in Istanbul. Each strain in logarithmic phase of growth was exposed to concentrations of antibiotics equal to minimum inhibitory concentration (MIC) and 4× MIC for 1 h.