Publications by authors named "Ayse Irem Sofuoglu"

Background: Little is known about mucocutaneous involvement in critically ill patients with the multisystem inflammatory syndrome in children (MIS-C). The aim of our study was to describe the localisation and variety of rash and to investigate whether presenting with rash at admission alters the clinical course of MIS-C.

Methods: This prospective, observational cohort study was conducted amongst children under 18 years of age who were admitted to our paediatric intensive care unit (PICU) between May 2020 and May 2021 with a possible diagnosis of MIS-C.

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Article Synopsis
  • COVID-19 primarily causes respiratory symptoms, but a small number of children can develop Multisystem Inflammatory Syndrome (MIS-C) after infection, which can lead to neurological issues.
  • A case was reported of a child with MIS-C who experienced cerebellar lesions and encephalopathy, showing worsening neurological symptoms like ataxia and dysarthria during the illness.
  • This case is significant as it is the first documented instance of a child with MIS-C developing cerebellar lesions on MRI, indicating possible cerebellitis.
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Background: Coronavirus disease 2019 may have neurological manifestations including meningitis, encephalitis, post-infectious brainstem encephalitis and Guillain-Barre syndrome. Neuroinflammation has been claimed as a possible cause. Here, we present a child with multisystem inflammatory syndrome in children (MIS-C) who developed pseudotumor cerebri syndrome (PTCS) during the disease course.

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Background: The coronavirus disease 2019 pandemic was caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although the predominant clinical presentation is a respiratory disease, neurologic manifestations are being recognized increasingly.

Case Report: We report 2 children 9 years of age who developed acute disseminated encephalomyelitis-like disease associated with SARS-CoV-2.

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