Publications by authors named "Ayse Gokce Erman"
Host metabolic fitness is a critical determinant of infectious disease outcomes. Obesity, aging, and other related metabolic disorders are recognized as high-risk disease modifiers for respiratory infections, including coronavirus infections, though the underlying mechanisms remain unknown. Our study highlights fatty acid-binding protein 4 (FABP4), a key regulator of metabolic dysfunction and inflammation, as a modulator of SARS-CoV-2 pathogenesis, correlating strongly with disease severity in COVID-19 patients.
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- The study examines the role of the Liver X Receptor Beta (LXRB) protein in brain cholesterol metabolism and its potential link to autism spectrum disorder (ASD) by exploring specific genetic variations (SNPs).
- It involved a comparison of lipid profiles and oxysterol levels between 107 children with ASD and 103 healthy children, revealing significant differences in cholesterol levels.
- The research suggests that imbalances in oxysterol metabolism could be a contributing factor to ASD, although the genetic variations studied did not show significant differences between the two groups.
This study describes an efficient and reusable process for ethanol production from medium containing whey powder, using alginate immobilized ethanologenic E. coli strains either expressing (TS3) or not expressing (FBR5) Vitreoscilla hemoglobin. Reuseabilities of the FBR5 and TS3 strains were investigated regarding their ethanol production capacities over the course of 15 successive 96-h batch fermentations.
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