Publications by authors named "Ayse D Yalcin"

Purpose: Levetiracetam (LEV) is an anti-seizure drug (ASD). A consensus has not been reached regarding its effects on bone health. This cross sectional study was planned to assess short, medium and long-term effects on bone density and blood parameters that are associated with bone metabolism.

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Article Synopsis
  • The study investigates the relationship between headaches and idiopathic/genetic epilepsy (I/GE) in patients aged 6-40 years, focusing on headache prevalence and characteristics among these individuals.
  • Out of 809 patients, 62.8% reported headaches, with 87.4% experiencing interictal headaches and 41.2% having migraines; the analysis identified distinct clusters based on headache and epilepsy features for both adults and children/adolescents.
  • Two primary clusters emerged: one included patients with a family history of headaches and specific seizure types (like juvenile myoclonic epilepsy), while the other contained patients with different characteristics, including those with self-limited epilepsy and generalized tonic-clonic seizures. *
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Epileptic vertigo is often a diagnostic problem. We aimed to present the clinical and electrophysiological features of patients with epileptic vertigo with a view to addressing the pathophysiology of this rare aura symptom. Nine epileptic vertigo patients were included in the study.

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Neurofibrillar tangles formed by the accumulation of hyperphosphorylated tau proteins in the intracellular space and the senile plaques formed by amyloid β (Aβ) accumulating in extracellular environment are shown as two main elements of Alzheimer's disease (AD). In our study, the relationship between the risk of Alzheimer's disease and TNFα rs1799724 polymorphism in the Turkish population was investigated. Our study is the first report investigating the relationship between the risk of Alzheimer's disease and TNFα rs1799724 gene polymorphism in Turkish population.

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Purpose: Pseudo-vestibular neuritis is a clinical diagnosis for patients presenting with acute vestibular syndrome due to a central pathology.

Case Report: We reported a case of multiple sclerosis characterized by pseudo-vestibular neuritis. Our case was a 32-year-old male patient.

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Purpose/aim Of The Study: Subacute sclerosing panencephalitis (SSPE) is a degenerative disease of the brain caused by a persistent measles virus infection occurring mostly in childhood or early adolescence. The spectrum of epileptic phenomena associated with SSPE is wide, varying from partial or generalized tonic-clonic seizures and atypical absences to myoclonic-atonic attacks. Tonic seizures are very rare in SSPE.

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Article Synopsis
  • * A case study of a 52-year-old man highlights his long history of treatment-resistant epilepsy, starting with lip twitching at age six and convulsive seizures by age 20.
  • * The report details EEG observations showing two unusual seizure patterns: preserved consciousness without absence seizures and instances where lip twitching was tonic instead of the typical myoclonic movements associated with POMA.
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Objectives: Crohn's Disease (CD) is a chronic systemic inflammatory disease associated with various extraintestinal manifestations, including seizure as a neurological finding. In this study, the prevalence of seizure and electroencephalographic abnormalities in patients with CD was investigated.

Materials And Methods: This study involved 41 patients with CD (female/male: 25/16) and 39 subjects in the control group (female/male: 25/14).

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Introduction: Mutations in the C19orf12 gene cause mitochondrial membrane protein associated neurodegeneration (MPAN), an autosomal recessive form of neurodegeneration with brain iron accumulation (NBIA). A limited number of patients with C19orf12 mutations, particularly those with adult onset of symptoms, have been reported.

Methods: We sequenced the entire coding region of C19orf12 in 15 Turkish adult probands with idiopathic NBIA.

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Objective: Vestibular migraine (VM) is a clinical condition characterized by temporal overlap between vestibular symptoms and migraine. In this study, we aimed to determine the changes in vestibular myogenic potential (cVEMP) and auditory brainstem response (ABR) in patients with VM and migraine.

Materials And Methods: A total of 86 participants with no hearing loss or additional disease between the ages of 18 and 45 were enrolled in three different groups: group 1, VM; group 2, migraine without aura; and group 3, healthy controls.

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Diabetic polyneuropathy is the most common neurologic complication of diabetes mellitus. Underlying mechanisms of diabetic polyneuropathy are related to various metabolic and inflammatory pathways. Pentraxin 3 (PTX3) is an acute phase protein that is produced locally at the inflammatory sites by several cell types.

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