The Self-Assessment, Perturbation, and Resonance Values of Voice and Speech in Individuals with Snoring and Obstructive Sleep Apnea.

Purpose: The static and dynamic soft tissue changes resulting in hypopnea and/or apnea in the subjects with obstructive sleep apnea (OSA) occur in the upper airway, which also serves as the voice or speech tract. In this study, we looked for the Voice Handicap Index-10 (VHI-10) and Voice-Related Quality of Life (V-RQOL) scores in addition to perturbation and formant values of the vowels in those with snoring and OSA.

Methods: Epworth Sleepiness Scale (ESS), STOP-Bang scores, Body-Mass Index (BMI), neck circumference (NC), modified Mallampati Index, tonsil size, Apnea-Hypopnea Index, VHI-10 and V-RQOL scores, perturbation and formant values, and fundamental frequency of the voice samples were taken to evaluate.

Relationships of orexigenic and anorexigenic hormones with body fat distribution in patients with obstructive sleep apnea syndrome.

Purpose: We aimed to examine the relationships of disease activity and risk factors with serum levels of orexigenic and anorexigenic hormones in patients with obstructive sleep apnea syndrome (OSAS).

Methods: Fasting blood samples were taken for hormonal analysis of all participants, abdominal/neck bioimpedance measurements were recorded, and polysomnography (PSG) analyses were performed. According to the apnea-hypopnea index (AHI), 34 patients with newly diagnosed OSAS and 34 participants without OSAS were compared.

The evaluation of serum brain-derived neurotrophic factor and neurofilament light chain levels in patients with obstructive sleep apnea syndrome.

Objectives: This study aimed to compare serum levels of brain-derived neurotrophic factor (BDNF) and neurofilament light (NfL) chain in normal individuals and patients with mild and moderate-severe obstructive sleep apnea syndrome (OSAS).

Methods: We enrolled 81 subjects referred to Otorhinolaryngology (Ear-Nose-Throat), Gazi University Faculty of Medicine, between 2017 and 2019. Based on the severity of OSAS, patients were divided into three groups: group 1 with mild OSAS (apnea-hypopnea index [AHI] 5-15; n = 26), group 2 with moderate-severe OSAS (AHI > 15; n = 32), and group 3 with normal individuals (AHI scores < 5; n = 23).

The evaluation of serum tryptophan and kynurenine levels in patients with obstructive sleep apnea syndrome.

Purpose: The kynurenine (Kyn) pathway may play a role in certain physiological functions such as behavior, sleep, thermoregulation, and pregnancy. Tryptophan (Trp) is oxidized with tryptophan 2,3-dioxygenase and indolamine 2,3-dioxygenase (IDO). Under normal conditions, hepatic kynurenine is a transcription factor and IDO expression in healthy tissues is very low.

Canal wall down versus canal wall up surgeries in the treatment of middle ear cholesteatoma.

Background/aim: To compare outcomes of canal wall up (CWU) and canal wall down (CWD) techniques in the treatment of middle ear cholesteatoma.

Materials And Methods: Medical records of 76 patients who had a primary surgery due to middle ear cholesteatoma between July 2015 and November 2017 were reviewed retrospectively. Hearing thresholds, speech discrimination scores (SDS), recurrences, and revision surgeries of CWU and CWD surgeries were compared.

The effect of obstructive sleep apnea syndrome on the central auditory system.

Background/aim: Obstructive sleep apnea syndrome (OSAS) is a disease characterized by repeated hypoxia attacks during sleep. The effect of hypoxia on the central nervous system is a well-known entity. In this study we aimed to investigate the effect of OSAS on the central auditory system.

Does nasal congestion have a role in decreased resistance to regular CPAP usage?

Nasal obstruction is known to cause resistance to continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea syndrome (OSAS). In this paper, short- and long-term nasal congestion in OSAS patients receiving CPAP treatment were evaluated with acoustic rhinometry (AR). A total of 36 patients with moderate-to-severe OSAS, diagnosed with polysomnography were included in the study.

Evaluation of hearing functions in patients with euthyroid Hashimoto's thyroiditis.

Sensorineural hearing loss has been reported in various autoimmune diseases. The relationship between Hashimoto's thyroiditis (HT) and the auditory system has not been previously evaluated. In this study, we investigated the effect of euthyroid HT on the hearing ability of adult patients.

Increased carotid artery intima-media thickness in patients with tympanosclerosis: Common risk factors with atherosclerosis?

We investigated the relationship between tympanosclerosis, known atherosclerotic risk factors, and the intima-media thickness of bilateral carotid arteries using ultrasonography. A total of 122 patients admitted to our clinic with chronic otitis media between 2005 and 2010 were included in the study. The study group consisted of 61 patients with tympanosclerosis; the control group comprised 61 patients without tympanosclerosis.

Vestibular functions were found to be impaired in patients with moderate-to-severe obstructive sleep apnea.

Objectives/hypothesis: Obstructive sleep apnea (OSA) and balance disorders are common chronic diseases seen in the general population. The aim of this study was to evaluate vestibular functions in individuals with OSA.

Study Design: Cross-sectional clinical study.

Are systemic voriconazole and caspofungin ototoxic? An experimental study with rats.

Objectives: To determine whether systemic administration of voriconazole and caspofungin causes ototoxicity.

Methods: This study was conducted on 32 healthy male Wistar albino rats. The baseline auditory brainstem response (ABR) thresholds of all animals were obtained under general anesthesia.

Changes in the ocular and nasal cultures in patients who had undergone septoplasty.

Objective: The aim of the study was to evaluate the microbiologic changes that occurred in the nasal and ocular mucosa before and after surgery in patients who had undergone septoplasty.

Design Setting: Fifty-five patients who applied to our clinic with septal deviation were included in the study.

Methods: Before and after the operation, samples were taken from the ocular and inner nasal mucosa for cultures and direct microscopic evaluation and the microbiologic changes were compared.

An alternative model for stapedectomy training in residency program: sheep cadaver ear.

To determine the usefulness of sheep cadaver ear as a complementary model for training of stapedectomy at residency programs, 2 of our 4 year residents were included in the study and each operated 20 sheep ears. All routine steps of stapedectomy operation were performed, and their success and complication scores were recorded. Performance of residents for stapedectomy and teflon piston placement in sheep ears were evaluated by the authors.