Uneven geography of health opportunities among subsidized households: Illustrating healthcare accessibility and walkability for public rental housing in Seoul, Korea.

Planners and policymakers significantly consider providing suitable living environments for marginalized households, beyond creating affordable homes. Previous studies have explored various socioeconomic attributes of neighborhoods with public rental housing (PRH), particularly regarding education, job, and transportation opportunities; however, we have a limited understanding of health opportunities among such subsidized households. This study, therefore, explores the accessibility and spatial equity of emergency medical services (EMS) and primary health care (PHC) for PRH residents in Seoul, Korea.

Cancer screening through surface-enhanced Raman spectroscopy fingerprinting analysis of urinary metabolites using surface-carbonized silver nanowires on a filter membrane.

Background: Label-free surface-enhanced Raman spectroscopy (SERS)-based metabolic profiling has great potential for early cancer diagnosis, but further advancements in analytical methods and clinical evidence studies are required for clinical applications. To improve the cancer diagnostic accuracy of label-free SERS spectral analysis of complex biological fluids, it is necessary to obtain specifically enhanced SERS signals of cancer-related metabolites present at low concentrations.

Results: This study presents a novel 3D SERS sensor, comprising a surface-carbonized silver nanowire (AgNW)-stacked filter membrane, alongside an optimized urine/methanol/chloroform extraction technique, which specifically changes the molecular adsorption and orientation of aromatic metabolites onto SERS substrates.

Exploring the nexus between physical environments, resident preferences, and usage frequency of community centers: Evidence from two Korean neighborhoods in Seoul.

Community centers offer a public space for physical activities, attracting residents with diverse interests and abilities, and promoting social interaction and connection, which in turn enhances individuals' physical and mental fitness and fosters a sense of community. When exploring the correlation between community space accessibility and usage frequency, it is crucial to consider empirical evidence and resident preferences. Nevertheless, the role of physical environments in determining community center usage frequency, while also considering residents' inclination for effortless access, remains unclear.

Effects of Multifaceted Determinants on Individual Stress: The Mediating Role of Social Capital.

Stress substantially results in various negative health outcomes. While there is a nexus between social capital and individual stress, previous studies have primarily explored the direct relationship between them. Social capital may potentially have an indirect effect on perceived stress via social networking pathways that provide accessible resources.

Rapid and sensitive multiplex molecular diagnosis of respiratory pathogens using plasmonic isothermal RPA array chip.

The current clinically available multiplex molecular diagnostic technologies are difficult to apply to onsite diagnostic platforms due to their large and sophisticated instrumentation, long amplification times and limited number of simultaneous detections. We developed a plasmonic isothermal recombinase polymerase amplification (RPA) array chip for rapid and sensitive multiplex molecular detection. The 3D plasmonic substrate composed of Au nanoparticles (NPs) on dense Au nanopillars (NPOP) showed highly enhanced plasmon-enhanced fluorescence (PEF) of RPA products with long DNA amplicons (~200 bp).

Label-Free SERS Analysis of Urine Using a 3D-Stacked AgNW-Glass Fiber Filter Sensor for the Diagnosis of Pancreatic Cancer and Prostate Cancer.

Metabolomics shows tremendous potential for the early diagnosis and screening of cancer. For clinical application as an effective diagnostic tool, however, improved analytical methods for complex biological fluids are required. Here, we developed a reliable rapid urine analysis system based on surface-enhanced Raman spectroscopy (SERS) using 3D-stacked silver nanowires (AgNWs) on a glass fiber filter (GFF) sensor and applied it to the diagnosis of pancreatic cancer and prostate cancer.

Highly sensitive and repeatable DNA-SERS detection system using silver nanowires-glass fiber filter substrate.

This paper describes a new simple DNA detection method based on surface-enhanced Raman scattering (SERS) technology using a silver nanowire stacked-glass fiber filter substrate. In this system, DNA-intercalating dye (EVAGreen) and reference dye (ROX) are used together to improve the repeatability and reliability of the SERS signals. We found that the SERS signal of EVAGreen was reduced by intercalation into DNA amplicons of a polymerase chain reaction on the silver nanowire stacked-glass fiber filter substrate, whereas that of ROX stayed constant.

Does elderly safety matter? Associations between built environments and pedestrian crashes in Seoul, Korea.

Korea's elderly population is growing rapidly, as is attention to elderly pedestrian safety. Despite a consensus that the elderly are vulnerable to pedestrian safety issues, our understanding of the determinants of elderly pedestrian crashes is limited. This study explores which attributes of the built environment affect the risk of pedestrian accidents among the elderly, particularly with respect to injury severity, in Seoul, Korea.

Author Correction: Closed-type pre-treatment device for point-of-care testing of sputum.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.

Closed-type pre-treatment device for point-of-care testing of sputum.

The procedures and protocols for the pre-treatment of sputum specimens, mainly used for the diagnosis of pneumonia, are complex, labor intensive, and require skilled specialists working in a biosafety containment laboratory because of sample infectivity. In this study, we developed the first portable, low-power pre-treatment device that carries out all sputum pre-treatment procedures (liquefaction, homogenization, dissolution, and inactivation) in an enclosed space. Designed to simultaneously employ chemical and mechanical dissolution in the enclosed chamber, this device eliminates the risk of transmission and improves the effectiveness of sputum dissolution and pathogen detection.

The Impacts of Residential Segregation on Obesity.

Background: This study examined the association between residential segregation and obesity for Whites, African Americans, Hispanics, and Asians. This study considered 3 dimensions of residential segregation, isolation, dissimilarity, and concentration.

Methods: By combining individual-level data from the Behavioral Risk Factor Surveillance System and county-level data from the County Health Rankings and Roadmaps, the total sample size was 204,610 respondents (160,213 Whites, 21,865 African Americans, 18,027 Hispanics, and 4505 Asians) from 205 counties in the United States.

Silicon membrane filter designed by fluid dynamics simulation and near-field stress analysis for selective cell enrichment.

Selective cell enrichment technologies can play an important role in both diagnostic and therapeutic areas. However, currently used cell sorting techniques have difficulties in rapidly isolating only the desired target cells from a large volume of body fluids. In this work, we developed a filtering system that can quickly separate and highly concentrate cells from a large volume of solution, depending on their size, using a silicon membrane filter.

From Perception to Action: The Mediating Role of Parental Safety Concerns on Adolescents' Physical Activity.

Background: Parental safety concerns have been recognized as a critical determinant of adolescents' physical activity. However, it is still uncertain what factors relate to parental safety concern, and how they, in turn, affect adolescents' physical activity. This study explored the mediating relationships of parental safety concern on adolescents' physical activity by considering personal, social, and built environmental factors.