Cascade Synthesis in Water: Michael Addition/Hemiketalization/Retro-Claisen Fragmentation Catalyzed by CatAnionic Vesicular Nanoreactor from Dithiocarbamate.

N,N-didodecylammonium N,N-didodecyldithiocarbamate (AmDTC-CC) underwent self-assembly to form a CatAnionic vesicular nanoreactor in water. AmDTC-CC can be readily prepared by condensation between N,N-didodecylamine and carbon disulfide. Previously, the cascade Michael addition/hemiketalization/retro-Claisen fragmentation was reported, but it required petroleum-based organic solvents as reaction media.