Development and characterization of a self-nano emulsifying drug delivery system (SNEDDS) for Ornidazole to improve solubility and oral bioavailability of BCS class II drugs.

This study aimed to investigate the in vitro performance of self-nanoemulsifying drug delivery systems (SNEDDSs) of Ornidazole (ORD), a poorly water-soluble drug. Self-nanoemulsifying drug delivery systems of ORD were prepared using various oils, non-ionic surfactants, and/or water-soluble co-solvents and assessed visually/by droplet size measurement. Equilibrium solubility of ORD in the anhydrous and diluted SNEDDS was conducted to achieve the maximum drug loading.

Changes in the rhizosphere and root-associated bacteria community of white Guinea yam ( Poir.) impacted by genotype and nitrogen fertilization.

The bacterial diversity and composition of water yam ( L. cv. A-19), which can grow without chemical fertilization, have recently been characterized with no significant differences compared with the use of chemical fertilization.

- Invited Review - Pig production in Africa: current status, challenges, prospects and opportunities.

Pig production is one of the viable enterprises of the livestock sub-sector of agriculture. It contributes significantly to the economy and animal protein supply to enhance food security in Africa and globally. This article explored the present status of pig production in Africa, the challenges, prospects and potentials.

Assessment of Biological Activities, Acute and Sub-chronic Toxicity of Liang (Gnetum gnemon var. tenerum) Leaves Powder, a Natural Product.

Gnetum gnemon var. tenerum (Gnetaceae) is a shrub plant native to South-East Asia. In Thailand, Liang leaves are commonly consumed in South of Thailand as vegetable.

Panel logit regression analysis of the effects of corruption on inflation pattern in the Economic Community of West African states.

It is widely believed that increase in money supply increases inflation rates in the long run. Dissenting evidences have later emerged to show that the inflation-money growth link has weakened over time. This study provides a political interpretation of inflation rates dynamics by investigating corruption as a potential risk factor associated with high inflation in the Economic Community of West African States (ECOWAS) using panel logit model.

Helicobacter pylori patient isolates from South Africa and Nigeria differ in virulence factor pathogenicity profile and associated gastric disease outcome.

Helicobacter pylori is a gram-negative, spiral-shaped bacterial pathogen and the causative agent for gastritis, peptic ulcer disease and classified as a WHO class I carcinogen. While the prevalence of H. pylori infections in Africa is among the highest in the world, the incidence of gastric cancer is comparably low.

Duodenal ulcer promoting gene (DupA), plasticity region genes and sigma factors in H. pyloristrains from Nigeria.

Introduction: Helicobacter pylori is a principal cause of gastric cancer. The aim of this study was to determine the prevalence and contribution of duodenal ulcer promoting gene A (dupA), the plasticity region genes and sigma factors in relation to their pathological expression of H. pylori infections in the Nigerian population.

Detection of Helicobacter pylori and its virulence genes (cagA, dupA, and vacA) among patients with gastroduodenal diseases in Chris Hani Baragwanath Academic Hospital, South Africa.

Background: The global prevalence of H. pylori approaches 50%, with prevalence rates between 20 and 40% in developed countries and up to 90% in Africa and other developing nations of the world. Development of H.

Prevalence of Helicobacter pylori infection among dyspeptic patients with and without type 2 diabetes mellitus in Nigeria.

Background: This multicenter study was undertaken to determine the prevalence of Helicobacter pylori (H. pylori) infection among dyspeptic patients with and without type 2 diabetes mellitus (T2DM).

Methods: Patients with dyspepsia were recruited from tertiary teaching hospitals, three in the South-West and one in the South-South regions of Nigeria, between November 2016 and August 2017.

Effect of temperature and distance on the viral outcome of clinical specimens from acute flaccid paralysis cases in Nigeria.

Aim: The effect of cold box temperature and distance on virus titers, poliovirus isolation rate, and appearance of orphan polioviruses was investigated.

Methods: Cold boxes with stools were randomly selected and examined for internal temperature over a 7-month period. After virus isolation in Rhabdomyosarcoma (RD) cell line RDand L20B, titer calculations and intratypic differentiation were done on isolates.

Removable partial denture design: a study of a selected population in Saudi Arabia.

Determination of the incidence of various classes of removable partial dentures (RPDs) including their designs and their comparison with previous studies provide clinically useful information for dental training and continuing education. The purpose of this study is to determine the pattern of partial edentulism, the major connector, clasping, and design of 740 cobalt chromium RPD frameworks constructed for a selected population in Saudi Arabia. RPD framework design information and patient personal data were obtained from the work authorization form and the dental records respectively.