Preparation of poly(hydroxyethyl methacrylate) cryogels containing L-histidine for insulin recognition.

In the present study, affinity adsorption technique was studied for insulin adsorption. Firstly, insulin-imprinted supermacroporous cryogel was prepared for the insulin adsorption. N-methacryloyl-(L)-histidine methyl ester (MAH) was chosen as the monomer.