Publications by authors named "Aynur Abdullah"
Article Synopsis
- Paxlovid is a new FDA-approved COVID-19 treatment, but its widespread use may lead to harmful interactions with other drugs.
- The study tested how Paxlovid interacts with 100 commonly prescribed small molecule drugs using a liver cell line to assess toxicity levels.
- Four significant interactions were identified, with two increasing toxicity and two decreasing it, leading to further analysis using molecular docking to understand these effects on Caspase-8, an important protein involved in cell death.
Antibiotic resistance is a significant threat to the human race, as regular consumption of antibiotics may lead to antibiotic-resistant bacterial strains. Non-antibiotic drugs also have an extensive impact on bacterial strains, where persistent uptake alters the survival mechanisms of bacteria that could lead to cross-resistance towards other antibiotics. Here, we use time-lapse proteomics shift assays to examine Gram-negative (E.
View Article and Find Full Text PDF