Publications by authors named "Aynaz Zarghampour"

The research aimed to investigate the solubility and thermodynamics of salicylic acid in two binary solvent mixtures of (1-propanol+propylene glycol) and (ethylene glycol monomethyl ether+1-propanol). The study was conducted in the temperature range of 293.2 to 313.

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Article Synopsis
  • - This study investigates how solubility and thermodynamics of salicylic acid change when mixed with binary solvent combinations (2-propanol + ethylene glycol and 2-propanol + propylene glycol) over temperatures ranging from 293.2 to 313.2 K.
  • - Different cosolvency models, including van't Hoff and Jouyban-Acree, were utilized to analyze the solubility data, comparing back-calculated values with experimental results to evaluate accuracy.
  • - The research also calculated important thermodynamic parameters like Gibbs energy, enthalpy, and entropy, while measuring the density of saturated salicylic acid mixtures and modeling it using the Jouyban-Acree approach.
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In this study, the solubility of mesalazine was investigated in binary solvent mixtures of poly ethylene glycols 200/600 and water at temperatures ranging from 293.2K to 313.2K.

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This work focuses on physicochemical features of the choline chloride/propylene glycol deep eutectic solvent (DES) + water mixtures by determining their density values in mono- and mixed- states over various temperatures in the range of 293.15-318.15 K.

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A new set of solute parameters derived from a correlation model using Catalan parameters. The parameters represent the interaction of the solute with the mono-solvents at 298.15K.

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Solubility determination of poorly water-soluble drugs is pivotal for formulation scientists when they want to develop a liquid formulation. Performing such a test with different ratios of cosolvents with water is time-consuming and costly. The scarcity of solubility data for poorly water-soluble drugs increases the importance of developing correlation and prediction equations for these mixtures.

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