Publications by authors named "Aymeric Hennemann"
Article Synopsis
- Molecular targeted therapy for metastatic melanoma is generally safer than chemotherapy but can still cause serious side effects, including life-threatening toxicity.
- A case study is reported where a patient treated with dabrafenib and trametinib experienced intracranial hemorrhage.
- Physicians need to be vigilant about this rare complication, ensuring the source of bleeding is correctly identified, as it may indicate new melanoma metastasis, anticoagulation overdose, or uncontrolled high blood pressure.
Cancers (Basel)
July 2023
Article Synopsis
- The study examines the long-term effectiveness of immune checkpoint inhibitor (ICI) rechallenge in patients with advanced melanoma who previously responded to ICI treatment.
- A total of 85 patients participated, with a notable 54% showing a positive response to the rechallenge, including 35% achieving a complete response.
- However, safety concerns emerged, as 27% experienced adverse events, and those who underwent other treatments between ICI courses had lower response rates and shorter progression-free survival.
