Response Surface Method Based Modeling and Optimization of CMC-g Terpolymer Interpenetrating Network/Bentonite Superabsorbent Composite for Enhancing Water Retention.

Water shortages have become a serious issue, so the importance of developing innovative cellulose-based superabsorbent polymer (SAP) was experimentally assessed as an environmentally friendly alternative to acrylate-based SAPs for the optimization of water consumption. The development of a biodegradable superabsorbent hydrogel composite based on a graft copolymer of carboxymethyl cellulose (CMC) and mixtures of different comonomers such as an acrylamide--acrylic acid--2-acrylamido-2-methylpropanesulfonic acid (Am--AA--AMPS) CMC--TerPoly interpenetrating network was characterized by infrared spectroscopy (FT-IR), scan electron microscopy (SEM), atomic force microscope (AFM), thermal gravimetric analysis (TGA), and swelling capacity in different aqueous media. The optimized CMC--(TerPoly) composite showing outstanding superabsorbance with high water retention, the ratio of constituents, temperature, and pH effect on equilibrium swelling have been optimized by using multistage response surface methodology (RSM).

Cure rate of Helicobacter pylori infection in Egyptian children related to CYP2C19 gene polymorphism.

Objectives: This study was done in order to investigate the effect of CYP2C19 genetic polymorphism on the cure rate of children who received proton pump inhibitors (PPI)-based triple therapy for treating Helicobacter pylori (H. pylori) infection.

Methods: Participants included 100 children with H.