Effect of local application of platelet-rich fibrin scaffold loaded with simvastatin on peri-implant bone changes.

Aim: The purpose of this study was to compare the effects of autologous platelet-rich fibrin (PRF) alone and PRF loaded with SIM on peri-implant bone changes and implant stability in patients undergoing implant rehabilitation.

Settings And Design: This was a nonrandomized controlled split-mouth study.

Materials And Methods: The study included 8 males between the ages of 45 and 60 years.