Bile metabolic fingerprints distinguish biliary tract cancer from benign biliary diseases.

Background And Aims: Biliary tract cancers are aggressive gastrointestinal malignancies characterized by a dismal 5-year overall survival rate <20%. Current diagnostic modalities suffer from limitations regarding sensitivity and specificity. This study aimed to develop a bile metabolite-based platform for precise discrimination between malignant and benign biliary diseases.

Pt/NiFe-LDH hybrids for quantification and qualification of polyphenols.

Polyphenols with antioxidant properties are of significant interest in medical and pharmaceutical applications. Given the diverse range of activities of polyphenols in vivo, accurate detection of these compounds plays a crucial role in nutritional surveillance and pharmaceutical development. Yet, the efficient quantitation of polyphenol contents and qualification of monomer compositions present a notable challenge when studying polyphenol bioavailability.

Next Generation Sequencing and Comparative Genomic Analysis Reveal Extreme Plasticity of Two Strains HN1 and HN2.

is an important rice pathogen, thus the genomic and evolutionary history may be helpful to control this notorious pathogen. Here, we present two complete genomes of the strains HN1 and HN2, which were isolated from diseased rice seed in China. Average nucleotide identity (ANI) analysis shows greater than 99% similarity of the strains HN1 and HN2 with other published genomes.

A-to-I mRNA Editing in a Ferric Siderophore Receptor Improves Competition for Iron in Xanthomonas oryzae pv. .

Iron is an essential element for the growth and survival of pathogenic bacteria; however, it is not fully understood how bacteria sense and respond to iron deficiency or excess. In this study, we show that in Xanthomonas oryzae pv. senses extracytoplasmic iron and changes the hydrogen bonding network of ligand channel domains by adenosine-to-inosine (A-to-I) RNA editing.

Identification and Characterization of Rice Circular RNAs Responding to pv. Invasion.

Emerging roles of circular RNAs (circRNAs) in various biological processes have advanced our knowledge of transcriptional and posttranscriptional gene regulation. To date, no research has been conducted to explore their roles in the rice- pv. interaction.

sp. nov., isolated from cornfield soil.

Strain L22-9, a Gram-stain-negative and rod-shaped bacterium, motile by one polar flagellum, was isolated from cornfield soil in Bijie, Guizhou Province, PR China. Based on 16S rRNA gene sequences, it was identified as a species. Multilocus sequence analysis of concatenated 16S rRNA, , and gene sequences showed that strain L22-9 formed a clearly separated branch, located in a cluster together with LMG 21623, DSM 13647 and DSM 13194.

Genome Resource for sp. Strain L22-9: A Potential Novel Species with Antifungal Activity.

is a complex genus with increasing numbers of new species. Recently, we isolated sp. strain L22-9, which showed antifungal activity against several fungal phytopathogens.