New insights into the interactions between the antibiotic enrofloxacin and fish protein by spectroscopic, thermodynamic, and theoretical simulation approaches.

In this study, myofibrillar proteins (MPs) from crucian carp were utilized as a model to investigate the binding mechanism between fish proteins and antibiotic residues. Fluorescence quenching confirmed the static quenching (K = 1.89 × 10 M s, K = 1.

Underestimation of tetracycline antibiotic residues in chicken meat: The role of protein binding.

Interesting variations in the analyte content were observed in chicken samples contaminated with tetracycline antibiotics (TCs) following pretreatment with various enzymatic hydrolysis before quantification by conventional analytical methods. Compared with untreated samples, the detectable contents of three TCs in protease-treated samples were 1.51 to 2.

Deciphering the interactions between altertoxins and glutenin based on molecular dynamic simulation: inspiration from detection.

Background: Mycotoxin contamination of food has been gaining increasing attention. Hidden mycotoxins that interact with biological macromolecules in food could make the detection of mycotoxins less accurate, potentially leading to the underestimation of the total exposure risk. Interactions of the mycotoxins alternariol (AOH) and alternariol monomethyl ether (AME) with high-molecular glutenin were explored in this study.

The adsorption-desorption behavior of chlorothalonil in the cuticles of apple and red jujube.

The distribution fate of chlorothalonil (CHT) in the environment (soil and water) and fruits is controlled by the capacity of cuticles to adsorb and desorb CHT, which directly affects the safety of both the environment and fruits. Batch experiments were conducted to reveal the adsorption-desorption behaviors of CHT in the cuticles of apple and red jujube. The adsorption kinetics showed that both physisorption and chemisorption occurred during the adsorption process.

Degradation of carbofuran and acetamiprid in wolfberry by dielectric barrier discharge plasma: Kinetics, pathways, toxicity and molecular dynamics simulation.

Carbofuran and acetamiprid pose the highest residual risk among pesticides found in wolfberries. This study aimed to degrade these pesticides in wolfberries using a multi-array dielectric barrier discharge plasma (DBD), evaluate the impact on safety and quality and explore their degradation mechanism. The results showed that DBD treatment achieved 90.

Molecular insights on the binding of chlortetracycline to bovine casein and its effect on the thermostability of chlortetracycline.

Bovine casein was selected as a model protein to evaluate the impact of food matrix on the thermal degradation of antibiotics. Fluorescence quenching and isothermal titration calorimetry experiments revealed that chlortetracycline (CTC) could spontaneously bind to casein via hydrogen bonding and hydrophobic interactions. The amino acid residues forming the binding pocket were further identified using molecular docking, while saturation transfer difference NMR deciphered that the binding of CTC engages its -N(CH) group.

Interaction between Six Waxy Components in Summer Black Grapes () and Mancozeb and Its Effect on the Residue of Mancozeb.

Mancozeb, an antifungal typically used for the growth of fruits, has the characteristic of non-internal absorption, and has a risk of binding to the waxy components of fruits. This work investigated the interaction of pesticide molecules with the waxy layer on the grape surface and their effects on pesticide residues in grapes. The study observed significant changes in the compositions of the waxy layer on the grape surface after soaking in a mancozeb standard solution.

Facile extraction and determination of organophosphorus pesticides in vegetables via magnetic functionalized covalent organic framework nanocomposites.

Facile enrichment and determination of trace organophosphorus pesticides (OPPs) in foods has been a constantly pursuing goal in food safety field. Herein, Zr-immobilized covalent organic frameworks (FeO@COF@Zr) have been first constructed and utilized as the powerful adsorbents for magnetic solid-phase extraction (MSPE) of OPPs. Owing to the π-π stacking interaction, hydrogen bonding and Zr-phosphate coordination reaction, the composites exhibited excellent selectivity and superior affinity to OPPs.

β-Cyclodextrin-/AuNPs-functionalized covalent organic framework-based magnetic sorbent for solid phase extraction and determination of sulfonamides.

β-Cyclodextrin-functionalized magnetic covalent organic framework (FeO@COF@Au-β-CD) was developed as sorbent for magnetic solid phase extraction of trace sulfonamides in meat samples prior to HPLC-MS/MS analysis. The sorbent was synthesized by loading gold nanoparticles onto a FeO@COF surface and then functionalized by thiolated-β-cyclodextrin immobilization via Au-S bonding formation. The prepared composite material was employed for sulfonamides extraction.

Sulphonate functionalized covalent organic framework-based magnetic sorbent for effective solid phase extraction and determination of fluoroquinolones.

Most of the reported covalent organic frameworks (COFs) are hydrophobic, limiting their adsorption application in sample pretreatment field. In this work, sulphonate functionalized magnetic covalent organic frameworks (COFs) composites were first synthesized by loading gold nanoparticles on FeO@COF(TpBD) surface and then functionalized by sodium 3-mercaptopropanesulphonate immobilization via Au-S bonding formation (denoted as FeO@COF(TpBD)@Au-MPS nanocomposites), which were further utilized as adsorbents for magnetic solid-phase extraction (MSPE) of fluoroquinolones. Compared with FeO@COF(TpBD), the composites exhibited higher affinity to fluoroquinolones.