Predictive parameters of uncontrolled asthma in the real world: a prospective study.

Background: The ultimate goal of asthma management is to have complete control of the condition, yet the number of patients with uncontrolled asthma continues to rise. This study aims to determine the prevalence of uncontrolled asthma, identify predictive parameters, and compare MART and non-MART treatment regimes.

Methods: A prospective questionnaire was administered to 495 patients who signed the consent form.

Alamandin and especially melatonin attenuate pulmonary arterial hypertension induced by monocrotalin.

Background: Despite the available treatments, pulmonary arterial hypertension (PAH) prognosis is poor.

Objectives: We aimed to investigate the effects of the alamandine (ALA), melatonin (MEL), and ALA + MEL in PAH.

Methods: The rats were randomly divided into Control (n = 10), monocrotaline (MCT) (n = 12), ALA (n = 12), MEL (n = 12), and ALA + MEL (n = 12) groups.

Evaluation of airway responsiveness and pulmonary function test results among obese and non-obese patients with obstructive sleep apnea syndrome.

Objective: In this research, we aimed to elucidate the effect of obstructive sleep apnea syndrome (OSAS) and obesity on pulmonary volumes and bronchial hyperreactivity, and particularly the effect of supine position on pulmonary volume and functions.

Patients And Methods: This was a prospective, cross-sectional study with a total of 96 patients (age range, 20-65 years). Based on the body mass index (BMI) and Apnea-Hypopnea Index (AHI) scores, the patients were divided into four groups: Group 1: AHI≥15/h, BMI≥30 kg/m2 (n=24), Group 2: AHI≥15/h, BMI<30 kg/m2 (n=24), Group 3: AHI<15/h, BMI≥30 kg/m2 (n=24), and Group 4: AHI<15/h, BMI<30 kg/m2 (n=24).

Erratum: Microscopic Phase-Space Exploration Modeling of ^{258}Fm Spontaneous Fission [Phys. Rev. Lett. 118, 152501 (2017)].

This corrects the article DOI: 10.1103/PhysRevLett.118.

Microscopic Phase-Space Exploration Modeling of ^{258}Fm Spontaneous Fission.

We show that the total kinetic energy (TKE) of nuclei after the spontaneous fission of ^{258}Fm can be well reproduced using simple assumptions on the quantum collective phase space explored by the nucleus after passing the fission barrier. Assuming energy conservation and phase-space exploration according to the stochastic mean-field approach, a set of initial densities is generated. Each density is then evolved in time using the nuclear time-dependent density-functional theory with pairing.

Assessment of Palliative Care in Lung Cancer in Turkey.

Objective: To investigate the symptoms of lung cancer in Turkey and to evaluate approaches to alleviate these symptoms.

Subjects And Methods: This study included 1,245 lung cancer patients from 26 centers in Turkey. Demographic characteristics as well as information regarding the disease and treatments were obtained from medical records and patient interviews.

The effect of methyl palmitate on treatment of experimental asthma.

Objective: To determine the effects of methyl palmitate on murine model of chronic asthma.

Methods: The experimental study was conducted in the animal laboratory of DokuzEylul University, Turkey, from October to December, 2012, and comprised BALB/c mice whowere divided into four equal groups: three experimental and one control group. All groups except the control group were sensitised and challenged with ovalbumin.

The association of nocturia with sleep disorders and metabolic and chronic pulmonary conditions: data derived from the polysomnographic evaluations of 730 patients.

Aim: To evaluate the prevalence of nocturia among different degrees of obstructive sleep apnea (OSA) and its association with various clinical conditions.

Materials And Methods: In 730 OSA patients, the prevalence and frequency of nocturia was determined, and the association of nocturia with clinical and laboratory variables such as the apnea-hypopnea index (AHI), apnea duration, and minimum oxygen saturation and clinical conditions such as diabetes mellitus, coronary heart disease, and chronic obstructive pulmonary disease (COPD) was determined.

Results: The overall prevalence of nocturia (≥2 wakes/night) was 50.

Correlation between hippocampal sulcus width and severity of obstructive sleep apnea syndrome.

The aim of the present study was to evaluate the relationship between obstructive sleep apnea syndrome (OSAS) severity and the hippocampal sulcus width in a cohort of subjects with OSAS and controls. A total of 149 OSAS patients and 60 nonapneic controls were included in the study. Overnight polysomnograpy was performed in all patients.

Frequency and predictors of obesity hypoventilation in hospitalized patients at a tertiary health care institution.

Objectives: Patients with obesity hypoventilation syndrome (OHS) have significant morbidity and mortality. Early diagnosis and treatment is important and there are limited data on its prevalence and predictive factors. The objective of this observational study was to determine the frequency and predictors of OHS in hospitalized patients at a tertiary health care institution.

Cerebral oxygenation during sleep in patients with obstructive sleep apnea: a near-infrared spectroscopy study.

Objective: The aim of the present study was to investigate cerebral hemodynamics in patients with sleep-disordered breathing of variable severity using cerebral near-infrared spectroscopy.

Design: Prospective study.

Setting: Tertiary training and research hospital.

Carotid intima-media thickness increase in patients with habitual simple snoring and obstructive sleep apnea syndrome is associated with metabolic syndrome.

Objectives: Sleep disorders are emerging risk factors for atherosclerosis. Increased carotid intima-media thickness (CCA-IMT) is a surrogate marker of cardiovascular risk. The aim of the present study was to investigate the relationship between CCA-IMT and habitual simple snoring or obstructive sleep apnea syndrome (OSAS) and the other cardiovascular risk factors.

Clinical characteristics of obstructive sleep apnea syndrome in heart transplant recipients.

Aim: We investigated the prevalence and clinical characteristics of obstructive sleep apnea syndrome (OSAS) among heart transplantation patients.

Methods: Among 86 surviving patients of mean age 43.07 ± 13.

Sleep analysis of patients with nocturia and benign prostatic obstruction.

Objective: To analyze the timing of nocturia during sleep and its effect on sleep quality using the polysomnography (PSG) findings from patients with benign prostatic obstruction.

Methods: From August 2009 to August 2010, 20 patients diagnosed with benign prostatic obstruction were enrolled in the present study. The sleep evaluation was performed by PSG.

The relationship between socio-demographic characteristics of patients and diagnostic delay in acute pulmonary thromboembolism.

Background: In pulmonary thromboembolism (PE), delay to diagnosis is very common. In this study, we examined the role of patients and the socio-demographic characteristics in delayed diagnosis of PE.

Patients And Methods: We evaluated 156 PE patients for the dates of symptom onset, the dates of first visit to a health institution and diagnosis, signs and symptoms, and the socio-demographic characteristics.

Non-Markovian diffusion over a parabolic potential barrier: Influence of the friction-memory function.

The over-passing probability across an inverted parabolic potential barrier is investigated according to the classical and quantal generalized Langevin equations. It is shown that, in the classical case, the asymptotic value of the over-passing probability is determined by a single dominant root of the "characteristic function," and it is given by a simple expression. The expression for the over-passing probability is quite general, and details of dissipation mechanism and memory effects enter into the expression only through the dominant root of the characteristic equation.

Method for numerical simulation of two-term exponentially correlated colored noise.

A method for numerical simulation of two-term exponentially correlated colored noise is proposed. The method is an extension of traditional method for one-term exponentially correlated colored noise. The validity of the algorithm is tested by comparing numerical simulations with analytical results in two physical applications.

Eosinophilic bronchitis as a cause of chronic cough.

Eosinophilic bronchitis is a recently described condition in patients with chronic cough, sputum eosinophilia, normal spirometry and no evidence of bronchial hyperreactivity. The aim of the study was to assess the causes of chronic cough and to identify the prevalence of eosinophilic bronchitis as a cause of chronic cough. Thirty-six patients [mean age 45.

Mechanical and chemical spinodal instabilities in finite quantum systems.

Self-consistent quantum approaches are used to study the instabilities of finite nuclear systems. The frequencies of multipole density fluctuations are determined as a function of dilution and temperature for several isotopes. The spinodal region of the phase diagrams is determined, and it appears that instabilities are reduced by finite size effects.