[Genotyping of hepatitis A virus prevalent strains in Xinjiang Hetian of China in 2006].

Objective: To analysis the genotypes of wild type hepatitis A virus circulated in Xinjiang Hetian of China in 2006.

Methods: The Vp1-2A region of HAV genome was amplified and sequenced from serum samples collected in Xinjiang Hetian of China in 2006, and subjected to phylogenetic analysis by Neighbor Joining (NJ) method.

Results: The nucleotide sequence differences in the VP1-2A region among Xinjiang Hetian HAV strains ranged from 0%-3.

Hepatitis A outbreaks in China during 2006: application of molecular epidemiology.

Background: In China, hepatitis is a huge public health problem. Outbreaks of hepatitis A are the most frequent cause of acute hepatitis, and to date, few epidemiologic investigations or molecular surveillance studies have been performed.

Materials And Methods: In 2006, two major outbreaks of hepatitis A occurred, one in Guigang City, southern China, and the other in Hetian City, northwestern China.