Publications by authors named "Ayidana Kaierdebieke"
The objective of this study was to investigate self-medication behavior among Chinese adolescents aged 12-18 years and explore the factors associated with whether adolescents prioritize drug efficacy or safety when engaging in self-medication behavior. In 2021, a questionnaire investigation was conducted in the Chinese mainland using a multi-stage sampling approach. After a statistical description, logistic regression was used to analyze the factors associated with considering drug efficacy and safety.
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- Aflibercept, used for metastatic colorectal cancer, has unclear antiangiogenesis-related side effects, prompting a systematic review of its adverse events when combined with chemotherapy.
- The study included data from 2889 patients across 10 trials and showed notable adverse effects such as hypertension (44.2%) and proteinuria (31.3%) in single-arm studies, with higher risks noted in randomized controlled trials for hypertension and proteinuria.
- Statistical analyses confirmed the increased incidence rates of serious adverse events in patients treated with aflibercept, highlighting the need for careful monitoring during treatment.