Alpha-fetoprotein and its value for predicting pregnancy outcomes - a re-evaluation.

Introduction: Alpha-fetoprotein (AFP) concentrations can be determined framing others from invasively acquired amnion fluid (AF-AFP). While the biological role of AFP remains unclear it is well known that AFP-levels can be altered in connection with specific clinical and/or genetic alterations of the fetus.

Materials And Method: here a retrospective study based on 3,119 singleton and 56 twin pregnancies is presented.