Biochemical characterization of bioinspired nanosuspensions from Swertia chirayita extract and their therapeutic effects through nanotechnology approach.

Swertia chirayita is used as a traditional medicinal plant due to its pharmacological activities, including antioxidant, antidiabetic, antimicrobial, and cytotoxic. This study was aimed to evaluate the therapeutic efficacy of newly synthesized nanosuspensions from Swertia chirayita through nanotechnology for enhanced bioactivities. Biochemical characterization was carried out through spectroscopic analyses of HPLC and FTIR.

Diagnostic evaluation of heel prick newborn screening of thyroid stimulating hormone on dissociation-enhanced lanthanide fluorescence immunoassay with the establishment of reference value in Pakistani neonates.

Objective: To develop and validate a method on Dissociation Enhanced Lanthanide Fluorescence Immunoassay for neonatal heel prick blood human thyroid stimulating hormone and the establishment of its reference value in the local population.

Methods: The multi-centre cross-sectional validation study was conducted from September 2016 to September 2018 at Zahra Beau Naqvi Foundation Welfare Trust laboratory, Islamabad, Pakistan, and comprised samples related to newborns aged 1 month or less taken from neonatal units of 39 hospitals based in Punjab, Khyber Pakhtunkhuwa, Gilgit-Baltistan and Azad Jammu and Kashmir. Samples were collected after 24 hours of birth using the heel prick test.

Novel Cellulose Triacetate (CTA)/Cellulose Diacetate (CDA) Blend Membranes Enhanced by Amine Functionalized ZIF-8 for CO Separation.

Currently, cellulose acetate (CA) membranes dominate membrane-based CO separation for natural gas purification due to their economical and green nature. However, their lower CO permeability and ease of plasticization are the drawbacks. To overcome these weaknesses, we have developed high-performance mixed matrix membranes (MMMs) consisting of cellulose triacetate (CTA), cellulose diacetate (CDA), and amine functionalized zeolitic imidazolate frameworks (NH-ZIF-8) for CO separation.

Performance Analysis of Blended Membranes of Cellulose Acetate with Variable Degree of Acetylation for CO/CH Separation.

The separation and capture of CO have become an urgent and important agenda because of the CO-induced global warming and the requirement of industrial products. Membrane-based technologies have proven to be a promising alternative for CO separations. To make the gas-separation membrane process more competitive, productive membrane with high gas permeability and high selectivity is crucial.

Evaluation of essential clinical components and features of current acne global grading scales.

Background: Acne research is hindered by the absence of a universal, consistently applied standard for severity grading. Acne experts recently identified 4 essential clinical components and 2 features for an ideal acne global grading scale (AGGS).

Objective: This study evaluated current AGGSs against consensus criteria previously identified as necessary.