Incidence and progression of ankle osteoarthritis: The johnston county osteoarthritis project.

Objective: To determine the incidence and progression of ankle osteoarthritis (OA) and associated risk factors in a community-based cohort of African Americans and whites.

Methods: Data were from 541 participants who had standardized lateral and mortise radiography of the ankles in weight bearing at baseline (2013-2015) and follow-up (2017-2018). Incident radiographic ankle OA (rAOA) was defined as a Kellgren-Lawrence grade (KLG) ≥ 1 at follow-up among ankles with baseline KLG < 1; progressive rAOA was a ≥ 1 KLG increase at follow-up among ankles with KLG ≥ 1 at baseline.

Temporal Trends and Factors Associated with Bisphosphonate Discontinuation and Restart.

Adverse events related to long-term use of bisphosphonates have raised interest in temporary drug discontinuation. Trends in bisphosphonate discontinuation and restart, as well factors associated with these decisions, are not fully understood at a population level. We investigated temporal trends of bisphosphonate discontinuation from 2010 to 2015 and identified factors associated with discontinuation and restart of osteoporosis therapy.

Trigeminal Neuralgia Secondary to Vertebrobasilar Dolichoectasia Treated with Cyberknife Stereotactic Radiosurgery.

Trigeminal neuralgia caused by vertebrobasilar dolichoectasia is a rare condition. It is characterized by paroxysmal hemifacial pain which is lancinating in type mostly refractory to medical management. This is a report of trigeminal neuralgia secondary to vertebral dolicholectasia refractory to medical management treated with cyber knife stereotactic radiosurgery to the dose of 66 Gy in single fraction to the proximal nerve root.

Improving drug adherence in osteoporosis: an update on more recent studies.

Similar to other chronic diseases such as diabetes and hypertension, osteoporosis has struggled with suboptimal medication adherence, resulting in an increased risk of fractures and all-cause mortality. The goal of this narrative review was to summarize interventions to improve medication adherence in osteoporosis. Because past reviews of this topic covered published literature through 2013, we conducted our literature search to include the period between January 2012 and November 2017.

Synthesis, structural, and photoluminescence studies of Gd(terpy)(H2O)(NO3)2M(CN)2 (M = Au, Ag) complexes: multiple emissions from intra- and intermolecular excimers and exciplexes.

The highly luminescent bimetallic cyanide materials, Gd(terpy)(H(2)O)(NO(3))(2)M(CN)(2) (M = Au, Ag; GdAu and GdAg, respectively) are quick and easy to synthesize under ambient conditions. A characteristic feature exhibited by both solid-state compounds is an intense red emission when excited with UV light. Additionally, GdAu exhibits a broad-band green emission upon excitation in the near UV region.

Emission enhancement through dual donor sensitization: modulation of structural and spectroscopic properties in a series of europium tetracyanoplatinates.

The synthesis of three different europium tetracyanoplatinates all incorporating 2,2':6',2''-terpyridine (terpy) have been carried out in acetonitrile/water mixtures by reaction of Eu(3+) salts with terpy and potassium tetracyanoplatinate. The use of different Eu(3+) sources results in the isolation of Eu(C(15)H(11)N(3))(H(2)O)(2)(NO(3))(Pt(CN)(4)) x CH(3)CN (1), {Eu(C(15)H(11)N(3))(H(2)O)(3)}(2)(Pt(CN)(4))(3) x 2 H(2)O (2), or [Eu(C(15)H(11)N(3))(H(2)O)(2)(CH(3)COO)(2)](2)Pt(CN)(4) x 3 H(2)O (3) for the nitrate, triflate, or acetate salts, respectively. All three compounds have been prepared as colorless crystals, and single-crystal X-ray diffraction has been used to investigate their structural features.