Publications by authors named "Aye Thida"

Extranodal marginal zone lymphoma (EMZL) is a rare subtype of non-Hodgkin's lymphoma characterized by the malignant transformation of lymphoid tissue at sites affected by chronic inflammation. Pleural marginal zone lymphoma (PMZL) is an infrequent manifestation of this condition. We report a case of PMZL co-occurring with primary lung adenocarcinoma.

View Article and Find Full Text PDF

Kaposi sarcoma (KS) is an angioproliferative disorder caused by human herpesvirus-8 (HHV-8) infection. KS manifests as vascular and mucosal nodules and is classified into four subtypes based on epidemiology, clinical presentation, histopathology, and HHV-8/human immunodeficiency virus serology. Here, we present a unique case of classic KS in an 84-year-old immunocompetent Haitian male patient, highlighting the rarity of this variant in this population.

View Article and Find Full Text PDF

Esophageal and gastroesophageal junction (GEJ) malignancies are aggressive, and survival is poor once metastasis occurs. The most common sites of metastatic involvement include the liver, lymph nodes, lung, peritoneum, adrenal glands, bone, and brain, while skeletal muscle (SM) involvement is rare. We report a case of a 68-year-old female who presented with intractable emesis for one month and was found to have a primary GEJ adenocarcinoma measuring up to 6.

View Article and Find Full Text PDF

Schwannomas are benign tumors arising from well-differentiated Schwann cells of peripheral nerves. They are usually found on the limbs, head, and neck. It is uncommon for schwannoma to occur in the pelvis and when it does, it is often diagnosed late.

View Article and Find Full Text PDF

Gastric cancer perforation is a rare but life-threatening complication of gastric cancer. We present the case of a 53-year-old male with acquired immune deficiency syndrome (AIDS) who presented to the emergency department with severe abdominal pain, was found to have an acute abdomen, and was eventually diagnosed with gastric perforation due to metastatic gastric cancer. This case highlights the challenges in diagnosing and managing perforated gastric cancer and discusses the surgical management options, including the use of laparoscopic techniques and the role of chemotherapy, particularly hyperthermic intraperitoneal chemotherapy (HIPEC).

View Article and Find Full Text PDF
Article Synopsis
  • Enterovirus D68 (EV-D68) is a reemerging virus linked to serious respiratory infections and paralysis, mainly affecting children, with outbreaks reported in various regions since 2014 but not in Southeast Asia until now.
  • A study in Myanmar collected nasopharyngeal swabs from children aged 1 month to 12 years admitted with acute lower respiratory infections, using a specialized PCR method to detect EV-D68.
  • The study found EV-D68 in 42 out of 570 samples (7.4%), with all strains identified as clade B3, marking the first detection of this virus in children in Yangon and highlighting the need for ongoing surveillance in Southeast Asia.
View Article and Find Full Text PDF

Over the decades, the global tuberculosis (TB) response has evolved from sanatoria-based treatment to DOTS (Directly Observed Therapy Shortcourse) strategy and the more recent End TB Strategy. The WHO South-East Asia Region, which accounted for 45% of new TB patients and 50% of deaths globally in 2021, is pivotal to the global fight against TB. "Accelerate Efforts to End TB" by 2030 was adopted as a South-East Asia Regional Flagship Priority (RFP) in 2017.

View Article and Find Full Text PDF
Article Synopsis
  • Parechovirus-A (PeV-A) is an emerging virus affecting children, with symptoms varying by genotype, but research has mostly focused on developed countries, leaving a knowledge gap in places like Myanmar.* -
  • This study analyzed nasopharyngeal samples from hospitalized children aged 1 month to 12 years at Yankin Children Hospital over two years to detect and genotype PeV-A.* -
  • Out of 570 samples, 11 were positive for PeV-A, revealing four different genotypes in Myanmar, with a median patient age of 10 months, indicating the need for further research on its clinical effects.*
View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to explore the link between the SNP rs7903146 in the TCF7L2 gene and the risk of type 2 diabetes mellitus (T2DM) in the Myanmar population.
  • By comparing 100 individuals with T2DM to 113 healthy controls, researchers found that carrier genotypes (CT and TT) had a significantly higher incidence in those with diabetes.
  • Results indicated that the T allele increases diabetes risk more than the C allele and is associated with lower pancreatic beta-cell function, highlighting its potential impact on T2DM management.
View Article and Find Full Text PDF

A 51-year-old male presented with intermittent chest pain for one month and productive cough with yellow sputum for seven days. He had a history of chronic kidney disease stage G3, depression, and polysubstance abuse. His chest X-ray revealed mild hazy opacity in the right lower lobe, followed by a chest computed tomography without contrast that indicated multiple nodular opacities in the left mainstem bronchus with clear lungs.

View Article and Find Full Text PDF

A 57-year-old woman with a history of hypertension, diabetes mellitus, obesity, asthma, and hemoglobin SC disease presented to the emergency department by her home health aide after she was found having altered mental status. According to her home health aide, the patient was responding with "Ok" to her questions for more than a day. The hemoglobin on admission was 8.

View Article and Find Full Text PDF

A 58-year-old male with a history of hypertension, dyslipidemia, osteoarthritis of both knees, and morbid obesity presented to the emergency department for opioid detoxification. He complained of generalized soreness, anxiety, and difficulty sleeping but denied signs and symptoms suggestive of coronavirus disease 2019 (COVID-19) infection. His COVID-19 polymerase chain reaction (PCR) result came back positive, and his D-dimer level was 5373 ng/mL.

View Article and Find Full Text PDF

A 19-year-old African American woman presented to the emergency department with a history of left upper quadrant pain for a week, associated with nausea, malaise, loss of appetite, subjective fevers and chills. Her family history is significant for thalassemia in her maternal aunt, and hereditary spherocytosis in her brother, sister and cousin. A contrast-enhanced CT scan of the abdomen and pelvis revealed massive splenomegaly and multiple splenic infarcts.

View Article and Find Full Text PDF

Background: The outcomes from an antiretroviral treatment (ART) program within the public sector in Myanmar have not been reported. This study documents retention and the risk factors for attrition in a large ART public health program in Myanmar.

Methods: A retrospective analysis of a cohort of adult patients enrolled in the Integrated HIV Care (IHC) Program between June 2005 and October 2011 and followed up until April 2012 is presented.

View Article and Find Full Text PDF

White matter hyperintensities (WMHs) of the brain are important markers of aging and small-vessel disease. WMHs are rare in healthy children and, when observed, often occur with comorbid neuroinflammatory or vasculitic processes. Here, we describe a complex 4 kb deletion in 2q36.

View Article and Find Full Text PDF

Co-infection with the hepatitis C virus (HCV) and/or hepatitis B virus (HBV) influences the morbidity and mortality of patients with HIV. A cross sectional analysis was of 11,032 HIV-infected patients enrolled in the Integrated HIV Care Program from May 2005 to April 2012 and Epi-info 3.5 was used to determine the serological prevalence of chronic hepatitis B and hepatitis C.

View Article and Find Full Text PDF