The Effect of Quetiapine on Treatment of Experimental Acute Spinal Cord Injury.

Aim: It is well known that treatment modalities against secondary damage due to spinal cord injury (SCI) are very important. This phase has been researched in many experimental studies. Apoptosis is one of the major mechanisms of secondary damage on spinal cord.

Primary Intracerebral Alveolar Soft Part Sarcoma in an 11-Year-Old Girl: Case Report and Review of the Literature.

Alveolar soft part sarcoma (ASPS), a rarely observed tumor, is a soft tissue sarcoma with an unidentified cell origin. It constitutes 0.5-1.

Results of radiosurgery for trigeminal neuralgia: Ankara experience.

Object: The purpose of this retrospective study is to demonstrate the effectiveness of Gamma Knife radiosurgery for essential trigeminal neuralgia (TGN) and assess the long-term outcome in a cohort from Turkey.

Methods: From 2004 to 2011, 93 cases of essential TGN were treated with single radiosurgery (RS). Female:male ratio was 45:48 and the mean age of the population was 57.

Accuracy of pedicle screw placement in thoracolumbar spine with conventional open technique.

Aim: To demonstrate the incidence of screw misplacement and revision rates in a group of 72 patients that underwent pedicle screw fixation for spinal pathologies using the conventional, fluoroscopy-guided open technique.

Material And Methods: Data from 72 consecutive patients with spinal instability that received 472 screws between April 2011 and May 2013 were reviewed and pedicle wall breach was graded as mild ( < 3 mm), moderate (3-6 mm) and severe ( > 6 mm). Direction of misplacement was also assessed in reformatted images as medial, lateral, superior and inferior (or in combinations).

Effectiveness of single posterior decompressive laminectomy in symptomatic lumbar spinal stenosis: a retrospective study.

Aim: The best method for surgical intervention in symptomatic lumbar stenosis is not clear. The present study aims to assess first year outcomes and complication rates of patients treated with single posterior decompressive laminectomy.

Material And Methods: Patients requiring surgery for severe, symptomatic, lumbar spinal stenosis were evaluated retrospectively.

Intraventricular dysembryoplastic neuroepithelial tumour: case report.

Dysembryoplastic neuroepithelial tumour (DNT) is located in the cerebral cortex with very few exceptions. In this article, an extremely rare case of intraventricular DNT originating from the septum pellucidum is reported. A 25-year-old woman presented with 5-month history of headache.

Neuroprotective effects of gabapentin in experimental spinal cord injury.

Background: Extensive research has focused on neuroprotection after spinal cord trauma to alleviate the effects of secondary injury. This study aims to investigate the neuroprotective effects of gabapentin in experimental spinal cord injury.

Methods: Thirty-six adult, male Wistar rats received spinal cord injury using the clip compression method.

Intracerebral tension pneumocephalus complicating endoscopic sinus surgery: case report.

Background: Various forms of intracranial air have been described in the literature.

Aim: This report aims to present clinical, radiological and intraoperative findings of a rare intracranial air entrapment case after endoscopic sinus surgery.

Ultrastructure protection and attenuation of lipid peroxidation after blockade of presynaptic release of glutamate by lamotrigine in experimental spinal cord injury.

Object: Lamotrigine is an antiepileptic drug that inhibits presynaptic voltage-gated sodium channels and reduces the presynaptic release of glutamate in pathological states. Neuroprotective effects of this drug have already been demonstrated in cerebral ischemia models. The aim of the present study was to determine the effects of presynaptic glutamate release inhibition on experimental spinal cord injury (SCI).

The effects of caffeine on L-arginine metabolism in the brain of rats.

In our study, the short-term effects of caffeine on L-arginine metabolism in the brains of rats were investigated. Caffeine was given orally at two different doses: 30 mg/kg and 100 mg/kg (a high non-toxic dose). Brain tissue arginase activity in rats from the caffeine-treated groups decreased significantly compared with the control group.

Epidural air entrapment after spinal surgery.

A case which had developed neurological complication because of compression due to air trapping in the epidural space after spinal surgery is presented with its clinical and radiological findings. Nitrous oxide can easily diffuse into the air-filled spaces in the body from the bloodstream and also increases the pressure of the air in the closed spaces. After the L4-5 discectomy procedure, weakness in dorsal flexion was occurred on the contra lateral leg.

Intrathecal gadolinium (gadopentetate dimeglumine)-enhanced MR cisternography used to determine potential communication between the cerebrospinal fluid pathways and intracranial arachnoid cysts.

This study was designed to assess the feasibility of intrathecal gadolinium-enhanced magnetic resonance cisternography (MRC) for the evaluation of the presence or absence of communication of cranial arachnoid cysts with the cerebrospinal fluid (CSF) pathways of the central nervous system (CNS). This prospective study included 20 patients (12 males and 8 females) with a mean age of 37 years, who had, as a group, 22 intracranial arachnoid cysts identified on prior CT and/or MR examinations. Routine pre-contrast cranial MR imaging was followed by the intrathecal administration of 0.

Effectiveness of FK506 on lipid peroxidation in the spinal cord following experimental traumatic injury.

Study Design: An in vivo study in Wistar albino rats with injured spinal cord.

Setting: Department of Neurosurgery, Biochemistry and Pathology, Gazi University, Ankara, Turkey.

Objectives: The aim of this study was to investigate and compare the effects of FK506 an immunosupressive agent with methylprednisolone (MP) on lipid peroxidation (LP) in injured spinal cord tissue.