Ultrastructural Alterations of Liver Tissue Cells in Methotrexate-Treated Balb/c Mice.

Aim: The current study investigated the efficacy of methotrexate (MTX) on liver tissue cells of Balb/c mice at the ultrastructural level using transmission electron microscopy.

Background: This agent is well known and used as a chemotherapeutic agent for a long time and not selective for cancer cells so, healthy cells beside cancer cells are also affected by MTX.

Materials And Methods: Experimental animals were divided into two groups; the first group was kept without treatment and served as the control, the second group was treated with 115 mg/kg MTX i.

An ultrastructural study, effects of Proteus vulgaris OX19 on the rabbit spleen cells.

Effects of Proteus vulgaris OX19 on the spleen cells of rabbits were investigated. Control group (n=5) and Proteus treated group (n=5) of New Zealand male rabbits were used in this study. Bacteria were injected to the rabbits in five days periods with increasing dosages for one month.

The variation of the amount of the neurosecretory materials in the Corpus Allatum of Pimpla turionellae L. (Hymenoptera: ichneumonidae) during oocyte maturation.

The purpose of this study is to examine the effects of neurosecretory material (NSM) in Corpus Allatum (CA) of endoparasitic Pimpla turionellae L. on reproduction. For this purpose, the egg maturation of the insect and the amount of the NSM in CA of the serial section of the brain were studied.