The effect of hypothermia on adnexal torsion/detorsion injury in a rat ovary model.

Purpose: Much attention has been given to hypothermia as it is effective in inhibiting inflammatory responses and also ischemia/reperfusion injury. Therefore, the aim of this study was to evaluate the effect of hypothermia on torsion/detorsion injury in rats.

Methods: Twenty-eight rats were randomly divided into four groups of sham-operated (SG), adnexal torsion/detorsion group (TG), adnexal torsion/detorsion+hypothermia group (THG) and hypothermia group (HG).

The relationship between platelet indices and clinical features of coronary artery disease.

Background: Platelets play a key role in the development and progression of cardiovascular disease. The degree of platelet activation may be assessed by platelet indices such as platelet count, mean platelet volume (MPV) and platelet distribution width (PDW).

Aim: To evaluate the relationship between platelet indices and clinical features of coronary artery disease (CAD).

A new hemoglobin variant: Hb Izmir [β86(F2)Ala→Val, GCC>GTC; HBB:c.260C>T].

We report a new hemoglobin (Hb) variant [β86(F2)Ala→Val; HBB:c.260C>T] that we have named Hb Izmir. We have identified Hb Izmir in a Turkish woman by ion exchange high performance liquid chromatography (HPLC) during a premarital screening program in the Aegean region of Turkey.

Expression and methylation pattern of p16 in neuroblastoma tumorigenesis.

Understanding migration, population and differentiation of primordial neural crest cells will help in evolving biology of neuroblastoma. P16 is a tumour suppressor gene contributing in cell cycle arrest as cyclin dependent kinase inhibitor. Methylation is an important mechanism for silencing tumor suppressor genes.

Inverse relationship between adiponectin and plasminogen activator inhibitor-1 in metabolic syndrome patients.

Objectives: To determine the serum levels of adiponectin and plasminogen activator inhibitor-1 in metabolic syndrome versus healthy controls and to see the relation of them with each other and with the metabolic syndrome components.

Methods: Adiponectin and plasminogen activator inhibitor-1 levels were measured in 53 subjects with metabolic syndrome and 30 healthy controls by ELISA. All subjects of metabolic syndrome had the criterias of metabolic syndrome (obesity, insulin resistance, hypertension, dyslipidemia, glucose metabolism disorders).