Publications by authors named "Ayaz Aghayev"

Background: Many research investigations for pulmonary embolism (PE) rely on the International Classification of Diseases 10th Revision (ICD-10) codes for analyses of electronic databases. The validity of ICD-10 codes in identifying PE remains uncertain.

Objectives: The objective of this study was to validate an algorithm to efficiently identify pulmonary embolism using ICD-10 codes.

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This document summarizes the relevant literature for the selection of the initial imaging in five clinical scenarios in patients with suspected or known nonvariceal upper gastrointestinal bleeding (UGIB). These clinical scenarios include suspected nonvariceal UGIB without endoscopy performed; endoscopically confirmed nonvariceal UGIB with clear source but treatment not possible or continued bleeding after endoscopic treatment; endoscopically confirmed nonvariceal UGIB without a confirmed source; suspected nonvariceal UGIB with negative endoscopy; and postsurgical or post-traumatic nonvariceal UGIB when endoscopy is contraindicated. The appropriateness of imaging modalities as they apply to each clinical scenario is rated as usually appropriate, may be appropriate, and usually not appropriate to assist the selection of the most appropriate imaging modality in the corresponding clinical scenarios of nonvariceal UGIB.

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Article Synopsis
  • Pulmonary artery aneurysms (PAAs) are uncommon but significant vascular issues that can present with vague symptoms, with some patients being asymptomatic while others may experience chest pain or difficulty breathing.
  • PAAs can be caused by various factors including congenital conditions, acquired factors, and unknown origins, with giant cell arteritis (GCA) being a rare cause outlined in limited case reports.
  • This case series presents an analysis of four patients diagnosed with isolated PAAs attributed to GCA, focusing on their clinical presentations, diagnostic imaging techniques, and treatment options.
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Abdominal aortic aneurysm (AAA) is a significant vascular disease found in 4% to 8% of the screening population. If ruptured, its mortality rate is between 75% and 90%, and it accounts for up to 5% of sudden deaths in the United States. Therefore, screening of AAA while asymptomatic has been a crucial portion of preventive health care worldwide.

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Pulmonary arteriovenous malformations (PAVMs) occur in 30% to 50% of patients with hereditary hemorrhagic telangiectasia. Clinical presentations vary from asymptomatic disease to complications resulting from the right to left shunting of blood through the PAVM such as paradoxical stroke, brain abscesses, hypoxemia, and cardiac failure. Radiology plays an important role both in the diagnosis and treatment of PAVM.

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Different types of vasculitis can be distinguished according to the blood vessel's size that is preferentially affected: large-vessel, medium-vessel, and small-vessel vasculitides. Giant cell arteritis (GCA) and Takayasu's arteritis (TAK) are the main forms of large-vessel vasculitis, and may lead to lumen narrowing. Clinical manifestations of arterial narrowing on the short- and long term include vision loss, stroke, limb ischemia, and heart failure.

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Article Synopsis
  • The article reviews various surgical and endovascular interventions related to different sections of the aorta, including the root, ascending aorta, arch, descending aorta, and abdominal aorta.
  • It emphasizes the significance of computed tomography angiography for accurate assessment and understanding of these procedures.
  • The discussion includes postsurgical findings and potential complications, making it a valuable resource for radiologists seeking to understand aortic interventions and their imaging needs.
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  • The inferior vena cava (IVC) and superior vena cava play crucial roles in returning blood from the body to the heart, and interruptions in these vessels can lead to stasis and increased risk of deep vein thrombosis (DVT) and pulmonary embolism (PE).
  • This study reviewed causes of IVC and superior vena cava interruption, including congenital issues like IVC agenesis, which heightens the risk of DVT, especially in younger patients.
  • Modern management predominantly involves vena cava filters for patients at risk of thromboembolism who cannot take anticoagulants, moving away from older surgical methods that posed significant risks and complications.
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This document discusses preprocedural planning for transcatheter aortic valve replacement, evaluating the imaging modalities used in initial imaging for preprocedure planning under two variants 1) Preintervention planning for transcatheter aortic valve replacement: assessment of aortic root; and 2) Preintervention planning for transcatheter aortic valve replacement: assessment of supravalvular aorta and vascular access. US echocardiography transesophageal, MRI heart function and morphology without and with IV contrast, MRI heart function and morphology without IV contrast and CT heart function and morphology with IV contrast are usually appropriate for assessment of aortic root. CTA chest with IV contrast, CTA abdomen and pelvis with IV contrast, CTA chest abdomen pelvis with IV contrast are usually appropriate for assessment of supravalvular aorta and vascular access.

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The creation and maintenance of a dialysis access is vital for the reduction of morbidity, mortality, and cost of treatment for end stage renal disease patients. One's longevity on dialysis is directly dependent upon the quality of dialysis. This quality hinges on the integrity and reliability of the access to the patient's vascular system.

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Derangements in the innate and adaptive immune responses observed in systemic inflammatory syndromes contributes to unique elevated atherosclerotic risk and incident cardiovascular disease. Novel multimodality imaging techniques may improve diagnostic precision for the screening and monitoring of disease activity. The integrated application of these technologies lead to earlier diagnosis and noninvasive monitoring of cardiac involvement in systemic inflammatory diseases that will aid in preclinical studies, enhance patient selection, and provide surrogate endpoints in clinical trials, thereby improving clinical outcomes.

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Magnetic resonance angiography (MRA) is a powerful tool for assessing upper and lower extremity artery pathologies. In addition to the classic advantages of MRA, such as the absence of radiation and iodinated contrast exposure, it can provide high temporal resolution/dynamic images of the arteries with high soft tissue contrast. Although it has a relatively lower spatial resolution than computed tomography angiography, MRA does not cause blooming artifacts in heavily calcified vessels, which is crucial in small vessel assessment.

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Article Synopsis
  • Cardiac magnetic resonance (CMR) is being evaluated for its ability to diagnose and predict outcomes in patients with ventricular arrhythmias, particularly its relation to sudden cardiac death (SCD).
  • In a study of 642 patients, abnormal CMR findings were found in 40% of those with nonsustained ventricular tachycardia (NSVT) and 66% of those with sustained ventricular tachycardia (VT) or aborted SCD, showing higher rates of major adverse cardiac events (MACE) associated with abnormal results.
  • The study concluded that incorporating CMR assessments can significantly enhance risk stratification in patients with ventricular arrhythmias, potentially leading to better management strategies.
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Background:  Contemporary pulmonary embolism (PE) research, in many cases, relies on data from electronic health records (EHRs) and administrative databases that use International Classification of Diseases (ICD) codes. Natural language processing (NLP) tools can be used for automated chart review and patient identification. However, there remains uncertainty with the validity of ICD-10 codes or NLP algorithms for patient identification.

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Arterial claudication is a common manifestation of peripheral artery disease. This document focuses on necessary imaging before revascularization for claudication. Appropriate use of ultrasound, invasive arteriography, MR angiography, and CT angiography are discussed.

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Breast cancer is the most common malignancy in women in the United States, with surgical options including lumpectomy and mastectomy followed by breast reconstruction. Deep inferior epigastric perforator (DIEP) flap is a muscle-sparing perforator free flap breast reconstruction technique, which uses the deep inferior epigastric artery (DIEA) perforators to create a vascular pedicle. Multiple perforators are identified by preoperative imaging, which are typically ranked based on size, location, and intramuscular course.

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  • This study evaluated the effectiveness of cardiac magnetic resonance techniques—specifically extracellular volume fraction (ECV) and global longitudinal strain (GLS)—in predicting outcomes for patients with suspected heart failure but no coronary artery disease.
  • Out of 474 patients monitored for an average of 18 months, 12% experienced all-cause death or heart failure hospitalization, with ECV and GLS showing significant associations with these outcomes even after adjusting for other factors.
  • The combination of ECV and GLS improved risk prediction models beyond traditional measures like left ventricular ejection fraction (LVEF) and late gadolinium enhancement (LGE), suggesting they could be valuable tools in heart failure risk assessment.
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  • Coronary artery calcium (CAC) scoring helps identify patients who might benefit from more aggressive treatments, but recent data on its influence on patient management is limited.
  • A study at Brigham and Women’s Hospital from 2015 to 2019 analyzed 839 patients to see how CAC testing affected medications and lifestyle changes.
  • Results showed that higher CAC scores led to increased prescriptions for aspirin, anti-hypertensives, and lipid-lowering therapy, especially for patients with significant calcification (CAC≥100), while more intense lifestyle recommendations were also correlated with higher scores.
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  • Infiltration of hemodialysis vascular access is a major issue that leads to high healthcare costs for dialysis patients.
  • Researchers used Ferumoxytol-enhanced magnetic resonance angiography to create detailed 3D models of vascular access without harmful contrast agents.
  • This new method allows for better pre-surgical planning, potentially lowering complications and costs associated with vascular access infiltration.
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