Protein adsorption behaviors onto Mn(II)-doped calcium hydroxyapatite particles with different morphologies.

Fundamental experiments on the adsorption behaviors of proteins onto plate-like and rod-like manganese-doped calcium hydroxyapatite particle (abbreviated as MnHAp) were examined. All of the obtained adsorption isotherms of bovine serum albumin (BSA) and lysozyme (LSZ) in a 1 × 10 mol/dm KCl solution were of the Langmuirian type. We found that the saturated amounts of the adsorbed BSA (n) increased with the increase in Mn/(Ca + Mn) atomic ratio (abbreviated as X) of the plate-like MnHAp, while the saturated amounts of adsorbed LSZ (n) decreased.