Uncertainty drives exploration of negative information across younger and older adults.

Although individuals generally avoid negative information, recent research documents that they voluntarily explore negative information to resolve uncertainty. However, it remains unclear (a) whether uncertainty facilitates exploration similarly when exploration is expected to lead to negative, neutral, or positive information, and (b) whether older adults seek negative information to reduce uncertainty like younger adults do. This study addresses the two issues across four experimental studies (N = 407).

Lutein Has a Positive Impact on Brain Health in Healthy Older Adults: A Systematic Review of Randomized Controlled Trials and Cohort Studies.

Unlabelled: A previous systematic review revealed that lutein intake leads to improved cognitive function among older adults. However, the association between lutein intake and brain health remains unclear.

Methods: We searched the Web of Science, PubMed, PsycInfo, and Cochrane Library for research papers.

The Role of Cognitive Control in Age-Related Changes in Well-Being.

Maintaining emotional well-being in late life is crucial for achieving successful and healthy aging. While previous research from Western cultures has documented that emotional well-being improves as individuals get older, previous research provided mixed evidence on the effects of age on well-being in Eastern Asian cultures. However, previous studies in East Asia do not always take into account the effects of cognitive control-an ability which has been considered as a key to enable older adults to regulate their emotions.

The non-steroidal anti-inflammatory drug diclofenac sodium induces abnormal embryogenesis and delayed lethal effects in early life stage zebrafish (Danio rerio).

Diclofenac sodium, a non-steroidal anti-inflammatory drug widely used in both human and veterinary medicine, has been detected in aquatic environments; therefore, its ecotoxicological effects on aquatic organisms need to be clarified. Recently, toxicity testing using zebrafish (Danio rerio) embryos has been recommended from the point of view of animal welfare; therefore, we investigated the suitability of using sub-lethal endpoints observed during embryogenesis for predicting lethal effects in early life stage zebrafish exposed to diclofenac sodium. After exposure to diclofenac sodium (0.

Curiosity in old age: A possible key to achieving adaptive aging.

Curiosity is a fundamental part of human motivation that supports a variety of human intellectual behaviors ranging from early learning in children to scientific discovery. However, there has been little attention paid to the role of curiosity in aging populations. By bringing together broad but sparse neuroscientific and psychological literature on curiosity and related concepts (e.

Lysophosphatidic acid in medicinal herbs enhances prostaglandin E and protects against indomethacin-induced gastric cell damage in vivo and in vitro.

Lysophosphatidic acid (LPA) is a bioactive phospholipid that induces diverse biological responses. Recently, we found that LPA ameliorates NSAIDs-induced gastric ulcer in mice. Here, we quantified LPA in 21 medicinal herbs used for treatment of gastrointestinal (GI) disorders.

Concentrated Phosphatidic Acid in Cereal Brans as Potential Protective Agents against Indomethacin-Induced Stomach Ulcer.

One of complications associated with long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) is peptic ulcer. Recently, we found that orally administered phosphatidic acid (PA) ameliorated aspirin-induced stomach lesions in mice. In this study, we identified PA-rich food sources and examined the effects of the food materials on indomethacin-induced stomach ulcer.

Development of an in vivo anti-androgenic activity detection assay using fenitrothion in Japanese medaka (Oryzias latipes).

The effects of endocrine disruptors, including anti-androgenic chemicals, on aquatic environments have received increased attention in recent years. Currently, the method used to screen chemicals for anti-androgenic activity is called the androgenized female stickleback screen, and it was established by the Organization of Economic Cooperation and Development in 2011 using the three-spined stickleback. However, screening chemicals for anti-androgenic activity has yet to be established using Japanese medaka.