Functional analysis of a first hindlimb positioning enhancer via expression.

During the early development of tetrapods, including humans, the embryonic body elongates caudally once the anterior-posterior axis is established. During this process, region-specific vertebral morphogenesis occurs, with the determination of limb positioning along the anterior-posterior axis. We previously reported that functions as an anatomical integration system that determines the positioning of hindlimbs and sacral vertebrae where is expressed.