Subretinal Fluid Drainage and Vitrectomy Are Helpful in Diagnosing and Treating Eyes with Advanced Coats' Disease.

Severe forms of Coats' disease are often associated with total retinal detachment, and a differential diagnosis from retinoblastoma is critically important. In such eyes, laser- and/or cryoablation is often ineffective or sometimes impossible to perform. We report a case of advanced Coats' disease in which a rapid pathological examination of subretinal fluid was effective for the diagnosis, and external subretinal drainage combined with vitrectomy was effective in preserving the eye.

Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin.

Objective: Lowering the blood concentration of low-density lipoprotein (LDL) cholesterol is the primary strategy employed in treating atherosclerotic disorders; however, most commonly prescribed statins prevent cardiovascular events in just 30% to 40% of treated patients. Therefore, additional treatment is required for patients in whom statins have been ineffective. In this study of atherosclerosis in rabbits, we examined the effect of probucol, a lipid-lowering drug with potent antioxidative effects, added to treatment with atorvastatin.

Efficacy of short-term postoperative perfluoro-n-octane tamponade for pediatric complex retinal detachment.

Purpose: To evaluate the efficacy of perfluoro-n-octane as a postoperative short-term tamponade after vitrectomy in pediatric cases with complex retinal detachment (RD) and proliferative vitreoretinopathy (PVR).

Design: Prospective, noncomparative, interventional case series.

Methods: The medical records of 10 eyes of 9 children (6 boys and 3 girls), whose age ranged from 3 months to 11 years, with a median of 7.

Persistence of retinal indocyanine green dye following vitreous surgery.

Background And Objective: To investigate the duration of postoperative persistence of indocyanine green (ICG) dye used during vitreous surgery.

Patients And Methods: Thirty-three patients (34 eyes) underwent macular surgery with removal of the internal limiting membrane (ILM) or epiretinal membrane using ICG dye to stain the membrane for better visualization. Infrared fundus photographs were taken postoperatively until infrared fluorescence had completely disappeared.

Better success of retinal reattachment with long-standing gas tamponade in highly myopic eyes.

Background: To evaluate the efficacy of long-term gas tamponade after pars plana vitrectomy (PPV) for retinal detachment (RD) due to a macular hole (MH) in highly myopic eyes.

Methods: A retrospective study was conducted at two institutions. The study included 25 highly myopic eyes with RD resulting from a MH.