Publications by authors named "Ayaka Takaori"

Article Synopsis
  • This study evaluated the effects of preoperative endoscopic ultrasound-guided tissue acquisition (EUS-TA) on patients with resectable or borderline resectable pancreatic cancer.
  • Data from 153 patients showed no significant differences in overall survival or positive peritoneal lavage cytology between those who underwent EUS-TA and those who did not.
  • The findings suggest that EUS-TA does not negatively affect postoperative survival or the rates of positive cytology in pancreatic cancer surgeries.
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Article Synopsis
  • The study investigated how neoadjuvant chemotherapy (NAC) affects gut microbiota in patients with resectable pancreatic ductal adenocarcinoma (PDAC).
  • Using stool samples from 20 patients, researchers analyzed microbiota changes before and after treatment, finding no significant differences in overall diversity.
  • Notably, they discovered a significant decrease in the Actinobacteria phylum post-NAC and an association between lower levels of Bifidobacterium and poorer tumor response to the chemotherapy.
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Objective Steroid pulse therapy is a regimen involving the intravenous administration of supra-pharmacological doses of corticosteroids in the short term. It is used to treat various inflammatory and autoimmune conditions. However, the strengths and limitations of steroid pulse therapy for induction of remission in type 1 autoimmune pancreatitis (AIP) are unknown.

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Objectives: We evaluated the preventive effect of low-dose diclofenac (25-50 mg) on post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) by propensity score matching analysis.

Methods: We retrospectively analyzed the data of 515 patients who underwent ERCP for the first time with or without the rectal administration of low-dose diclofenac before the procedure. For the purpose of minimization of the intrinsic selection bias, we compared the incidence rate of PEP between the diclofenac and control group after propensity score matching.

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