Publications by authors named "Ayaka Omori"
Article Synopsis
- Precordial Doppler ultrasound can confirm the correct placement of peripheral intravenous (PIV) access in children during surgery.
- The study investigated the minimum amount of normal saline (NS) needed for this confirmation, testing doses of 0.1 mL/kg, 0.3 mL/kg, and 0.5 mL/kg.
- Results showed that 0.3 mL/kg of NS is the minimal effective dose for accurately confirming correct PIV access, outperforming the lower dose of 0.1 mL/kg.
Article Synopsis
- Precordial Doppler ultrasound can confirm peripheral intravenous access in children by detecting sound changes after saline injection, but probe placement has varied in past research.
- This study aimed to identify whether the right or left parasternal border is a better location for the Doppler probe when assessing children's heartbeats.
- Results showed that the left parasternal border had a significantly higher detection rate of audible heartbeats compared to the right, suggesting it is the optimal probe placement site, contrary to previous findings.
Article Synopsis
- The study investigates the safety of using dexmedetomidine and propofol for sedation during cardiac catheterization in pediatric patients with Fontan circulation, focusing on upper airway obstruction and oxygen desaturation rates.
- Findings indicate that there is a high incidence of airway interventions (31.4%) and oxygen desaturation (28.6%) among these patients under sedation.
- Specific risk factors, such as a history of snoring, use of midazolam, and recent upper respiratory infection symptoms in young children, significantly increase the likelihood of airway obstruction.
The cerebral cortex is formed by diverse neurons generated sequentially from neural stem cells (NSCs). A clock mechanism has been suggested to underlie the temporal progression of NSCs, which is mainly defined by the transcriptome and the epigenetic state. However, what drives such a developmental clock remains elusive.
View Article and Find Full Text PDFBackground: Preventing pulmonary vascular remodeling is a key strategy for pulmonary hypertension (PH). Causes of PH include pulmonary vasoconstriction and inflammation. This study aimed to determine whether cilostazol (CLZ), a phosphodiesterase-3 inhibitor, prevents monocrotaline (MCT)- and chronic hypoxia (CH)-induced PH development in rats.
View Article and Find Full Text PDFNeural stem cells, called radial glia, maintain epithelial structure during the early neocortical development. The prevailing view claims that when radial glia first proliferate, their symmetric divisions require strict spindle orientation; its perturbation causes precocious neurogenesis and apoptosis. Here, we show that despite this conventional view, radial glia at the proliferative stage undergo normal symmetric divisions by regenerating an apical endfoot even if it is lost by oblique divisions.
View Article and Find Full Text PDF