Publications by authors named "Ayaka Ohno"
Febrile infection-related epilepsy syndrome (FIRES) is a rare epileptic encephalopathy that occurs in children or adolescents. To date, evidence for the management of the post-acute phase of FIRES is focused on drug-resistant epilepsy that continues from the acute phase. Information on involuntary movements, which are newly developed in the chronic phase, is limited.
View Article and Find Full Text PDFHigh bleeding risk (HBR), as defined by the Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria, has been recently reported to be associated with an increased risk of major bleeding events and cardiovascular events. We investigated the association between the ARC-HBR score and clinical outcomes in patients with stable coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI). We assessed 328 consecutive patients with stable CAD who underwent PCI between January 2017 and December 2020.
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- The study compared the effectiveness of three bleeding risk scoring systems (J-HBR, ARC-HBR, and PRECISE-DAPT) in predicting major bleeding events in patients who underwent percutaneous coronary intervention (PCI).
- Out of 646 patients analyzed, a significant number were identified at high bleeding risk according to each scoring system, with 44 patients experiencing major bleeding events during a median follow-up of 974 days.
- The results showed that all three scores had similar predictive abilities for major bleeding events in the short- and mid-term, with area under the curve (AUC) values indicating no significant differences among them.
Article Synopsis
- A study examined how pre-procedure frailty affects long-term outcomes in elderly patients (65+) with stable coronary artery disease undergoing elective percutaneous coronary intervention (PCI).
- Out of 239 patients assessed, 15.9% were classified as frail, and the research found that frail patients had a significantly higher risk of major adverse cardiovascular events (MACEs) compared to non-frail patients.
- The study concluded that pre-PCI frailty is an important predictor for increased risk of complications, including major bleeding events and MACEs, highlighting the need for careful consideration of frailty in elderly CAD patients undergoing PCI.
Background: Academic Research Consortium for High Bleeding Risk (ARC-HBR) criteria have been used to identify high-risk patients undergoing percutaneous coronary intervention (PCI) in current clinical practice. This study aimed to evaluate the association between the number of ARC-HBR criteria and clinical outcomes in patients with acute coronary syndrome (ACS) after an emergent PCI.
Methods: We assessed 338 consecutive patients with ACS who underwent successful emergent PCI between January 2017 and December 2020.
An efficient chemo-enzymatic process for construction of the α-linked disaccharide unit (GlcNAcα1-4Gal) found in gastric mucin has been developed. The process consists of a one-step preparation of a novel triazine type glycosyl donor in water and the subsequent transglycosylation to a galactose derivative catalysed by α-N-acetylglucosaminidase.
View Article and Find Full Text PDF1. Cannibalism can play a prominent role in the structuring and dynamics of ecological communities. Previous studies have emphasized the importance of size structure and density of cannibalistic species in shaping short- and long-term cannibalism dynamics, but our understanding of how predators influence cannibalism dynamics is limited.
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