Great Debates: Surgery or Watch and Wait After Total Neoadjuvant Therapy for Rectal Cancer.

Locally advanced rectal cancer has traditionally been treated with multimodal therapy including neoadjuvant chemoradiotherapy followed by surgical resection. More recent data suggests that in appropriate patients, total neoadjuvant treatment (TNT) makes it possible to adopt a "watch and wait" approach. Advocates for watch and wait argue that patients with a complete or near-complete clinical response to TNT have comparable overall and disease-free survival to their counterparts who undergo surgical resection, and also have a better quality of life, fewer complications, and potentially avoid a stoma.

The nature and prevalence of psychiatric disorders in a Sudanese juvenile correctional facility.

High morbidity of mental disorders among juvenile offenders has been confirmed by several studies, thus challenging both the juvenile justice system and the mental health system. Data from developed countries may not reflect the situation in low-income countries and therefore cannot form a basis for intervention. No similar study has been done in Sudan.