Infrastructure operation and maintenance is essential for societal safety, particularly in Japan where the aging of infrastructures built during the period of high economic growth is advancing. However, there are issues such as a shortage of engineers and inefficiencies in work, requiring improvements in efficiency and automation for their resolution. Nevertheless, there are still many inefficiencies in the current procedures for bridge inspections.
View Article and Find Full Text PDFThe present study examined localization of cholecystokinin receptor (CCK-R) mRNA in the muscle layer of the ovine omasum and role of CCK-R type 1 (CCK-1R) in the regulation of muscle contraction of the omasum. We demonstrated that not only CCK-R type 2 (CCK-2R) mRNA but also CCK-1R mRNA is highly expressed in the muscle layer of the ovine omasum. Application of CCK-8 to muscle strips of the greater curvature of the ovine omasum at 1-100 nM induced tonic contraction in a concentration-dependent manner, and the contractile effect of CCK-8 was inhibited by both CCK-1R antagonist lorglumide (IC(50) 2.
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