Analysis of immediate 503 thyroid carcinoma deaths: Trend of single institution in 2005-2024.

Background This study aimed to investigate the changes in the histological types and causes of death associated with thyroid carcinoma (TC) before and after the introduction of systemic drug therapy. Methods The records of 503 deceased patients treated for TC and with death from TC between January 2005 and June 2024 were reviewed in this retrospective cohort study. Multivariate logistic regression was applied to assess whether the number of patients with anaplastic TC (ATC) at the diagnosis and the number of local-related deaths changed before and after the introduction of Lenvatinib (i.

The CONUT Score Can Predict the Prognosis of Gastric Cancer Patients After Curative Treatment.

Background/aim: Malnutrition is a reported prognostic factor in patients with cancer. The controlling nutritional status (CONUT) score, an index calculated from routine laboratory tests, is correlated with the prognosis of various cancers. This study examined the relationship between the CONUT score and prognosis of patients with gastric cancer (GC) after radical gastrectomy.

Clinical Significance of Residual Lymph Node Metastasis in Predicting Recurrence After Preoperative Chemotherapy and Surgery for Gastric Cancer.

Background/aim: Neoadjuvant chemotherapy is gaining recognition for its potential to improve survival outcomes, with combined neoadjuvant and adjuvant therapies under investigation. However, the prognostic significance of post-chemotherapy pathological staging (ypStage) on recurrence-free survival (RFS) remains unclear. This study aimed to evaluate the utility of ypStage, ypT, ypN classification, and histological response rate in predicting recurrence after gastrectomy.

Clinicopathological Features and Prognosis of Unresectable Colorectal Cancer With the Mutation.

Background/aim: Patients with unresectable advanced and recurrent colorectal cancer (CRC) and the mutation have poor prognosis, and conventional chemotherapy is often ineffective. This study aimed to retrospectively evaluate the clinicopathological features and prognosis of this patient population.

Patients And Methods: We examined clinicopathological characteristics and treatment outcomes of 26 patients with -mutated unresectable advanced and recurrent CRC treated between June 2015 and October 2022.

The Hemoglobin, Albumin, Lymphocyte and Platelet (HALP) Score as an Independent Prognostic Factor for Esophageal Cancer Patients who Received Curative Treatment.

Background/aim: Esophageal cancer (EC) is a malignant tumor with poor prognosis. Prognostic factors that may be used in the treatment and management of EC are important. The purpose of this study was to evaluate the impact of the hemoglobin, albumin, lymphocyte, and platelet (HALP) score on the long-term oncological prognosis of patients with EC who have undergone curative treatment.

Ilio-Iliac Arteriovenous Fistula Secondary to a Ruptured Right Common Iliac Artery Aneurysm and Anomalous Anatomy of Inferior Vena Cava Resulting in an Arteriovenous Shunt Formation with Right-sided Cardiac Failure: A Case Report.

Introduction: An ilio-iliac arteriovenous fistula (IIAVF) secondary to the rupture of a common iliac artery aneurysm (CIAA) is rare. Sudden arteriovenous shunting and subsequent fistula enlargement can result in acute cardiac failure. Immediate diagnosis and treatment are required; however, the clinical symptoms differ from those of a free wall rupture of an aortic aneurysm, making a quick diagnosis difficult.

[Clinical Outcomes of Gastrectomy in Very Elderly Gastric Cancer Patients Over 90 Years of Age].

We investigated the clinical outcomes of gastrectomy in 7 patients over 90 years of age. Four patients were male and 3 were female. The tumor was located in the U region in 1 patient, M region in 2, and L region in 4.

[A Case of Huge Infectious Gastrointestinal Stromal Tumor of the Stomach Undergoing Primary Tumor Resection after Endoscopic Drainage].

A 77-year-old man presented to our hospital with anemia and was diagnosed with a high-risk gastrointestinal stromal tumor (GIST)of the stomach on abdominal CT scan and endoscopic ultrasound-guided fine-needle biopsy. One month after initiating the neoadjuvant imatinib therapy, the patient was admitted to our hospital for fever and was diagnosed with an intratumoral infection. Antibiotic therapy was immediately initiated, and upper gastrointestinal endoscopy revealed a fistula between the stomach and tumor; therefore, endoscopic drainage was performed through the fistula.

Impact of Perioperative Rehabilitation on Postoperative Length of Hospital Stay for Patients With Gastric Cancer.

Background/aim: Perioperative rehabilitation is effective in preventing postoperative complications and is associated with a shorter length of hospital stay after gastrectomy. However, its impact on short-term outcomes in patients without post-gastrectomy complications has not yet been clarified. This study aimed to evaluate the usefulness of perioperative rehabilitation beyond preventing postoperative complications.

Evaluation of Eye Alignment Before and After Refractive Surgery Using an Implantable Collamer Lens in Phakic Patients with Myopia.

Purpose: To investigate changes in eye alignment before and after ICL implantation in patients with myopia having corrected distance visual acuity (CDVA) of ≥0.0 logMAR.

Subjects And Methods: The medical records of 1012 patients without eye movement limitation who underwent bilateral ICL implantation were retrospectively reviewed a at the Eye Center of Sanno Hospital in Japan.

Risk factors for anastomotic leakage in rectal cancer surgery reflecting current practices.

Purpose: In recent years, major advancements have been made in rectal cancer surgery with the introduction of new techniques such as robotic surgery and indocyanine green fluorescence imaging (ICG-FI). This study aimed to evaluate the comprehensive risk factors for anastomotic leakage (AL) following rectal cancer surgery, incorporating recently introduced techniques and other existing factors, to reflect current practices.

Methods: A retrospective analysis was conducted of 304 patients who underwent either robotic or laparoscopic anterior resection between January 2019 and December 2023.

Long-term prognostic outcomes in high-risk T1 colorectal cancer: A multicentre retrospective comparison of surgery versus observation postendoscopic treatment.

Aim: The risk of lymph node metastasis after endoscopic resection of high-risk T1 colorectal cancer prompts additional resection. However, age and comorbidities are considered in decision-making and some surgeons opt for observation. We compared the long-term outcomes of these approaches with the aim of clarifying the need for additional resection.

The Global Immune-Nutrition-Information Index (GINI) Is an Independent Prognostic Factor for Esophageal Cancer Patients Who Receive Curative Treatment.

Background/aim: The aim of the present study was to evaluate the clinical impact of the Global Immune-Nutrition-Information Index (GINI) in patients with esophageal cancer (EC) who received curative treatment and to clarify the potential of the GINI as a prognostic factor.

Patients And Methods: Patients who underwent curative resection for EC at Yokohama City University between 2000 and 2020 were consecutively chosen based on their medical records. The GINI was defined as follows: GINI=[C-reactive protein×platelet×monocyte×neutrophil]/[albumin×lymphocyte].

Thyroid metastasis from ovarian clear cell carcinoma.

Summary: A 56-year-old woman with cervical pain with a history of ovarian clear cell carcinoma stage IIIC was admitted to a primary care doctor. Ultrasonography revealed a microhyperechoic nodule in the thyroid gland and cervical lymph node enlargement, and fine-needle aspiration was performed. The results showed malignancy, and she was admitted to our hospital.

[Infective Endocarditis Diagnosed After Acute Arterial Occlusion of the Lower Extremity:Report of a Case].

A 73-year-old male was admitted to our hospital due to fever and right lower limb pain. Contrast-enhanced computed tomography (CT) revealed occlusion from the right common femoral artery to the right superficial femoral artery and from the left common iliac artery to the left internal and external iliac arteries, leading to a diagnosis of bilateral acute arterial occlusion of the lower extremity. Emergency thrombectomy was performed to improve arterial blood flow.

Prognostic nutritional index is an independent risk factor for continuing S-1 adjuvant chemotherapy in patients with pancreatic cancer who received neoadjuvant chemotherapy and surgical resection.

Purpose: Reports on the association of perioperative nutritional and inflammatory status with the clinical course of adjuvant chemotherapy did not include neoadjuvant chemotherapy. We aimed to clarify the mechanism by which perioperative nutritional and inflammatory status affect the clinical course of postoperative adjuvant chemotherapy in patients with pancreatic cancer.

Methods: We enrolled 123 patients with pancreatic cancer retrospectively who underwent surgical resection with neoadjuvant and S-1 adjuvant chemotherapy between January 2013 and December 2022.

[A Case of Upper Gastrointestinal Perforation during Treatment with Regorafenib for Recurrent Rectal Cancer].

A 58-year-old man was treated with radical excision for rectal cancer. Pathological findings were pT3N1M0, Stage ⅢB, RAS: mutant, BRAF: mutant, MSS. The patient was followed up without adjuvant chemotherapy.