Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Prospective Studies.

Obstructive sleep apnea (OSA) is a prevalent clinical disorder characterized by intermittent airway obstruction during sleep, resulting in hypoxemia and hypercapnia. Although OSA is associated with increased cardiovascular disease (CVD) risk, such as hypertension, the precise nature of this relationship remains uncertain. This systematic review and meta-analysis aim to evaluate the potential links between OSA and cardiovascular outcomes by synthesizing data from recent prospective studies.

Primary Sjögren's syndrome without ocular manifestation: a case report.

Introduction And Importance: Sjögren's Syndrome is a systemic immune disorder, manifested in dry eyes and mouth. Primary Sjögren's syndrome without ocular manifestation is seldom mentioned in the literature.

Case Presentation: The authors report a case of a 48-year-old female who complained of dryness of mouth and dysphagia for 6 months.

Rilonacept and Anakinra in Recurrent Pericarditis: A Systematic Review and Meta-Analysis.

Interleukin 1 (IL-1) has been indicated as a mediator of recurrent pericarditis. Rilonacept, a soluble IL-1 receptor chimeric fusion protein neutralizing interleukin 1 alpha (IL-1α) and interleukin 1 beta (IL-1β), has demonstrated promising results in a phase II study in recurrent or refractory pericarditis. Anakinra is a recombinant inhibitor of the IL-1 receptor with a demonstrated reduction in the incidence of recurrent pericarditis.